The 100th Annual Canadian Chemistry Conference – A Celebration of Chemistry, May 28 – June 1, Toronto

Join us at the Canadian Chemistry Conference for several days’ worth of education, instrumentation news and networking. Our team will be both exhibiting and giving an oral presentation during the event. Visit booth #603 to view the latest advancements in single-quadrupole mass spectrometry, including:

    • The NEW inert atmospheric solids analysis probe (iASAP) for air sensitive compounds

    • The NEW design of the atmospheric solids analysis probe (ASAP) for solvent-free analysis of liquid and solid samples in less than 30 seconds

    • The NEW volatile APCI source for headspace analysis

We also encourage you to join colleague Lee Collier on Tuesday at 8AM for a poster session on the expression CMS in radiochemistry:

Using a Single Quad Mass Spectrometer in a Radiochemistry Lab
TL Collier, Advion Inc., S Liang and N Vasdev, Massachusetts General Hospital, Harvard Medical School

In the last few years the cost of a single quadrupole mass spectrometer (SQMS) has come down substantially and this reduction in price is making SQMS more affordable to researchers in academic settings and is now finding applications in radiochemistry laboratories. Since these SQMS are becoming available to a wider audience, the possible uses of this type of equipment may not be evident to all users.

The user of a SQMS in a simple LC system can provide basic information however, with the addition of some simple equipment – is it possible to improve the sensitivity and utility of the SQMS? In this presentation, we will focus on radiochemistry laboratories and non-traditional applications of SQMS, and how to modify most systems to obtain further information, including: 1? Identification of possible side products, 2) use of fragmentation ion source settings to obtain further structural information, 3) The determination of the parent ion and possible metabolites in plasma samples, 4) The use of a trap and release system to concentrate dilute samples to allow for the determination of molecular ions and metabolites, 5) quantitation and identification of the parent compound in solutions, 6) development of reformulation methodologies using cold standards – at levels that normally seen in PET or SPECT preparations.

For a first look at the iASAP probe, watch our latest product video now: