Mass Spec Solutions for Chemical Biology

Advion is the partner of choice for biopharmaceutical, academic/government researchers, and industrial chemists seeking to enhance their chemical synthesis knowledge, workflow and mass spectrometry results. Using our deep scientific and engineering expertise, we develop a broad portfolio of chemist-centric, purpose-built mass spectrometers, nanoelectrospray ionization sources, flow-chemistry synthesis systems and consumables characterized by their reliability, high quality and flexibility.

Quant Express, an addition to Advion’s user-friendly Mass Express 4.0 software suite, features quantitation to create a fully integrated software system for expression CMS users.

Learn More »

The vAPCI ion source for the expression CMS is a simple, powerful tool for gas phase sample analysis. The technique can quickly and confidently identify compounds in air, breath, headspace and other gas samples without the need for any sample preparation.

Learn More »

The inert ASAP (iASAP) allows easy sampling of air-sensitive compounds, such as metal catalysts and organometallics, from reactions that are carried out in a glove box or Schlenk line to prevent oxidation. The technique allows a synthetic chemist to perform real-time reaction monitoring.

Learn More »

The Chemist’s Detector

A high performance mass spec for every chemistry laboratory

Learn More »

Chip-based electrospray ionization technology

Combining the strengths of liquid chromatography, mass spectrometry, chip-based infusion, fraction collection, and direct surface analysis into one integrated system

Learn More »

Featured Applications

See more applications »

Natural products

Faster scan speed, online polarity switching and in-source CID to generate the information for compound identification and structural information of previously unknown natural product analytes.

Learn More »Natural products »

Reaction monitoring

The expression CMS addresses the need of organic and synthetic chemists to understand the optimal time to quench a reaction mixture. They can obtain answers within minutes rather than hours or days.

Learn More »Reaction monitoring »

Teaching chemistry

Advion offers a plug and play, compact, single quadrupole mass spectrometer designed specifically with the academic chemistry laboratory in mind, the expressionE CMS.

Learn More »Teaching chemistry »

Protein assays and peptide synthesis

Real-time reaction monitoring based on a combination of thin-layer chromatography (TLC) and compact mass spectrometry (CMS) is a simple and quick way for chemists to overcome synthetic challenges and optimize chemical reactions in the modern laboratory.

Learn More »Protein assays and peptide synthesis »

Success Stories

See more stories »

Research Analyst – University of Leiden

“I incorporated the expression CMS as a TLC/MS system because of its simplicity, low cost and the brilliant combination with the Plate Express.”

Dr. Hans van den Elst, Research Analyst, University of Leiden

Read More »

Department of Chemistry – Creighton University

“It’s easy, walk-up use with straightforward swapping of ESI and APCI sources make it a reliable, productive tool for determining synthetic success.”

Dr. Martin Hulce, Department of Chemistry, Creighton University

Read More »

Cyclotron and Radiochemistry Research Program – UNC School of Medicine

“The convenience of having a mass spectrometer in our laboratory means that we can increase working efficiencies.”

Dr. Zibo Li, Department of Radiology UNC School of Medicine

Read More »

Department for Homogeneous Catalysis, Max-Planck-Institut für Kohlenforschung

“Rapid characterization of reaction products combined with the lowest effort of sample preparation”

List Research Group, Max-Planck-Institut für Kohlenforschung

Read More »

Tides

April 30 - 3
San Diego, CA

Fort Detrick Tent Show

May 2 - 3
Frederick, MD

OMSS

May 17 - 18
Ohio

NIH Spring Research Festival

May 24 - 25
Bethesda, MD

Press Releases

See more releases »