Measurement of THC in Exhaled Breath after Marijuana Smoking: Exploring the Potential of a Transportable LC/CMS System

Dr. Jack Henion presents the possibility of using the Advion Interchim Scientific expression^® Compact Mass Spectrometer (CMS) for ‘roadside breath testing’ of THC DRUID (driving under the influence of drugs) with the use of a small plastic breath collection device from Breath Explor of Uppsala, Sweden. This device serves as a simple, acceptable collection device for individuals in contrast to venous puncture with a needle or other means of collecting a biological sample.

In this ASMS 2020 Reboot presentation, you will learn:

• Breath sample collection with the Breath Explor device
• The potential benefits and challenges of a roadside LC/CMS testing system including an automated robot for sample preparation with the Advion Interchim Scientific expression^® CMS and Advion Interchim Scientific AVANT UHPLC
• The Advion LC/CMS system provides accurate and sensitive results when used to analyze breath samples for THC

Authors: Olof Beck², Jack Henion¹, Sabina Seferaj², Peter Stamback^3
1Advion, Inc., Ithaca, NY
²Karolinska Institute, Stockholm, Sweden
³Breath Explore, Munkplast AB, Uppsala, Sweden