expression® CMS: Mass Spectrometers Designed for Chemists

With decades of mass spectrometry and chemistry expertise, Advion Interchim Scientific has produced a family of compact mass spectrometers designed for the chemist. The affordability, small size and ease of use make them ideal for use directly at the chemist’s bench, giving immediate answers and informed decisions instead of waiting.

The Advion Interchim Scientific expression® compact mass spectrometer (CMS) is a fast and easy analytical tool for the organic chemist. Ideal for fast reaction monitoring, the expression® CMS features a single quadrupole that can adapt to multiple ionization sources in seconds, including both ESI and APCI. The mass spectrometer works in a variety of applications, including food and beverage, pharmaceutical, biomedical, peptides and proteins, drug discovery and more. The expression® CMS offers a variety of novel sampling techniques, including:

  • Direct mass analysis of TLC plates in 30 seconds at the push of a button with Plate Express
  • One-touch analysis of solids and liquid samples with the ASAP® probe
  • LC/CMS
  • Many more options and configurations to suit your needs

Learn more about the different sample techniques available with the expression® CMS, including fast assay methods for liquids, solids, gases, and even air-sensitive compounds.

Fill out the form to download the full expression® CMS brochure now.

Screening of explosive residues without sample preparation using a direct sample analysis probe on the expression® CMS

The ability to effectively screen passengers with minimal personal contact is critical. Ion mobility detectors used at many airports can be inaccurate and provide many false-positives and false-negatives. Advanced Imaging Technology (AIT) screening techniques are very useful for detecting concealed weapons and explosive devices located on passengers and/or in their belongings, however are unable to detect trace amounts of explosive residues.

The expression® Compact Mass Spectrometer (CMS) with an Atmospheric Solids Analysis Probe (ASAP®) is a high performance instrument with a small footprint that allows airports to better screen for explosive residues on passengers and their belongings.

The expression® CMS provides rapid and accurate detection with significantly reduced false-positives and false-negatives than ion mobility instruments.

Direct Sample Analysis of “Fizzy Drinks”

Chemists are tasked with quickly identifying compounds created, ensuring quality of products or evaluating safety. Current techniques are adequate, but not all offer speed, data quality or ease-of-use provided by the expression® Compact Mass Spectrometer (CMS). The expression® CMS with the direct analysis probe (ASAP®) offers chemists the ability to rapidly analyze solids, liquids and powders without tedious and time consuming sample preparation.

Direct Analysis of Liquids and Solids

Direct sample analysis of liquids, solids and powders without chromatography is as easy as it sounds, and provides mass spectral information within seconds. The video demonstrates analysis of a reaction mixture.

Analysis of Two Reaction Products by Direct Analysis Probe on a Compact Mass Spectrometer

The expression CMS provides essential compound information quickly and improves the chemist’s workflow. The Atmospheric Solids Analysis Probe (ASAP®) permits fast analysis of solid and liquid samples and is a simple, low cost alternative to LC/MS methods. This direct analysis probe method has been shown to be useful for the analysis of volatile and semivolatile compounds. ASAP is available as a combined ASAP-APCI source, or existing APCI sources can be easily modified to become dual APCI-ASAP capable.

Register to download the full application note.

Reaction Monitoring by Direct Analysis Probe on a Compact Mass Spectrometer

The expression CMS provides essential compound information quickly and improves the chemist’s workflow. The Atmospheric Solids Analysis Probe (ASAP®) permits fast analysis of solid and liquid samples and is a simple, faster and lower cost alternative to LC/MS methods. This direct analysis probe method has been shown to be useful for the analysis of volatile and semivolatile compounds. ASAP is available as a combined ASAP-APCI source, or existing APCI sources can be easily modified to become dual APCI-ASAP capable.

Register to download the full application note which includes the results of an example analysis.