Simplifying the Flash Purification Process Leveraging TLC and Mass Spectrometry

The compound synthesis, purification and confirmation processes often present challenges. From ensuring successful synthesis of your product, setting up a flash purification method, and finally confirming ID of fractions, the lengthy work flow can be time consuming and repetitive.

This webinar will provide a foundation for flash purification processes, and will showcase a novel work flow concept that breaks down the process in to easy steps for optimal success. We will offer tips to optimize each essential segment of the workflow, and share seamless steps to quickly and easily drive the process from reaction monitoring to flash purification and fraction ID.

Presented by Dr. Daniel Eikel, Director of Customer Service and Product Applications, Advion.

This webinar was hosted by C&EN and recorded 8/13/20.

What’s in My Sample? Mass Spectrometry Instruments

Mass spectrometry is an analytical technique used to determine the mass-to-charge ratio of ions in a sample and therefore the sample composition. This method is used across many industries including food and beverage, environmental monitoring, and clinical. There are many features of mass spectrometers that must be considered before purchasing such as the required mass analyzer technology, ionization source, and dissociation technique. Join Lab Manager and our panel of experts as we discuss how to decipher mass spectrometry technology offerings and find the right solution for your lab.

As an attendee, you will learn more about:

  • Available technology for performing mass spectrometry
  • Features to consider when purchasing mass spectrometry instruments
  • How to find the right mass spectrometer for your application

Analyzing the World Around Us: Tools for Environmental Testing & Monitoring

Environmental monitoring is vital to understanding the world around us. Air quality, water, and soil testing all provide valuable information about an environment’s status. Tools and technologies for environmental monitoring can be used to evaluate the sanitation of a food and beverage lab or to monitor an ecosystem’s recovery after an oil spill. Join Lab Manager and our panel of experts as we review the tools available for environmental testing and monitoring.

As an attendee, you will learn more about:

  • Developments in technology for environmental testing and monitoring
  • Considerations when purchasing technology for environmental testing and monitoring
  • Applications for environmental testing and monitoring across industries

This webinar was hosted by Lab Manager Tech Trends and recorded July 9, 2020.

Food Science and Quality Control: Tools for Food & Beverage Testing

Lab Manager Tech Trends Webinar. Recorded June 25, 2020.

Food and beverage labs use techniques from other disciplines such as microbiology, environmental monitoring, and analytical chemistry to test for food and beverage contaminants. Unlike these disciplines, the food and beverage industry is highly regulated and therefore food and beverage labs have very specific needs. Join Lab Manager and our panel of experts as we discuss tools for food and beverage testing.

In this webinar, you will learn more about:

  • The latest technology for testing in the food and beverage lab
  • Applications for tools and technologies in the food and beverage lab
  • Considerations when purchasing instruments for food and beverage testing

Rapid Cannabinoid Testing Method for Cannabis Quality Control

A simple, sensitive and selective ASAP® sample introduction approach to measuring the presence of two isobaric compounds, CBDA and THCA, contained in a complex sample such as hemp or cannabis plants or their corresponding extraction products. Measurements are made of differences in the relative composition of CBDA and THCA fragment ions originating from the same precursor ion. Applicability to screening plants and plant product materials such as hemp or marijuana to monitor out-of-specification composition is demonstrated.

This application was developed from the poster presented at the 2018 Cannabis Science Conference in Portland, OR.

Intelligent Flash Purification: TLC Guided Purification and Mass Spectrometry

The combination of the Advion Interchim Scientific expression® CMS and puriFlash® flash chromatography technologies speed up the synthesis, purification and characterization of a compound.

Using the Advion Interchim Scientific expression® Compact Mass Spectrometer, the Plate Express TLC Plate reader, the ASAP® Atmospheric Solids Analysis Probe, and the puriFlash® XS520 flash purification system, it is now possible to execute a fast, user-friendly workflow to run TLC, harness the power of your cell phone to develop a flash method, and finally utilize a simple dipping probe to confirm fractions in seconds.

With easy sampling techniques, intuitive software, and advanced detection technology, you can easily and confidently synthesize, purify and characterize your compound, in a flash.

Intelligent Flash Purification using TLC and Mass Spectrometry

The compound synthesis, purification and confirmation process often presents challenges throughout. From ensuring successful synthesis of your product, setting up a flash purification method, and finally confirming ID of fractions, the lengthy work flow can be time consuming and repetitive.

In this application note, we demonstrate how the combination of Advion Interchim Scientific technologies speed up the synthesis, purification and characterization of a compound.

This series features the Advion Interchim Scientific expression® Compact Mass Spectrometer (CMS), the Plate Express TLC Plate Reader, the Atmospheric Solids Analysis Probe (ASAP®), and the puriFlash® XS520 flash purification system.

The Essential Systems & Consumables for Purification, Evaporation & Mass Spectrometry

The Advion Interchim Scientific suite of systems and consumables allows users to harness the power of mass spectrometry, flash chromatography, prep LC and more. Simple and robust, download our brochure to learn more about:

  • The Advion Interchim Scientific expression® compact mass spectrometer (CMS): A fast and easy analytical tool for the organic chemist. Ideal for fast reaction monitoring, the expression® CMS features a single quadrupole that can adapt to multiple ionization sources in seconds, including both ESI and APCI. The expression® CMS offers a variety of novel sampling techniques, including fast assay methods for liquids, solids, gases, and even air-sensitive compounds.
  • Direct mass analysis of TLC plates in 30 seconds at the push of a button with Plate Express
  • One-touch analysis of solids and liquid samples with the ASAP® probe
  • LC/CMS
  • puriFlash® ultra performance flash purification: Ideal for method development and purification of rare and high added value compounds, the Interchim family of puriFlash® systems offer users a wide range of throughput options and the highest recovery rates at >95%.
  • Mass-Guided Purification: the Interchim puriFlash® + Advion CMS offers the ideal solution for Flash-MS, and can provide fraction identification in <30 seconds.

Fill out the form to download the full Advion Interchim Scientific brochure now.

Rapid and Direct Screening for Vitamin E Acetate in E-Cigarette Juices by ASAP®/CMS

The recent outbreak of severe lung injury is allegedly tied to the presence of Vitamin E Acetate (VEA) in vaping-related products after VEA was found in lung fluid samples of patients with vaping-related lung illness (EVALI). Calling for regulatory control, Washington, Colorado and Ohio have already banned the use of VEA in e-juices at the state level.

The Advion Interchim Scientific expression® Compact Mass Spectrometer (CMS) with the Atmospheric Solids Analysis Probe (ASAP®) provides a highly sensitive screening method for the presence of VEA.