Analytical Sciences Synthesis & Purification: Consumables, Reagents & Instruments

The new edition of our “Analytical Sciences, Synthesis & Purification” catalog is available now! Offering a full suite of innovative products and technologies from Advion Interchim Scientific, this catalog features over 20,000 products ranging from consumables and reagents to instrumentation.

Not only a product resource, the catalog features in-depth scientific information to improve your daily workflow, including sample preparation tips and tricks, analysis technologies such as GC and LC/MS, and help selecting the best consumables for your workflow or purification.

Take advantage of this extensive guide to boost your lab with:

  • 20,000 Products
  • 12 Chapters
  • Technicals Tips
  • New Systems

Laboratory Insider: A Look Inside the Organic Synthesis Lab

Ask the Expert Webinar
Presented live November 2, 2022

Step inside the Parasram Lab at New York University for a look at some of their latest research.

In this webinar, Professor Marvin Parasram will discuss data from his laboratory’s recent publication, “Anaerobic Heteroatom Transfer Reactions Using Photoexcited Nitroarenes.” The research features developments on the anaerobic cleavage of alkenes into carbonyl compounds using nitroarenes as oxygen transfer reagents under visible light. This approach is a safe and practical alternative to mainstream oxidative cleavage protocols, such as ozonolysis and the Lemieux–Johnson reaction.

As an attendee, you will learn more about:

  • How a wide range of alkenes possessing oxidatively sensitive functionalities underwent anaerobic cleavage to generate carbonyl derivatives with high efficiency and regioselectivity, using the Advion Interchim Scientific puriFlash® 5.250 Preparative HPLC system.
  • Mechanistic studies support that the transformation occurs via direct photoexcitation of the nitroarene followed by a nonstereospecific radical cycloaddition event with alkenes.
    How this process leads to 1,3,2- and 1,4,2-dioxazolidine intermediates that fragment to give the carbonyl products, using the Advion Interchim Scientific expression Compact Mass Spectrometer.
  • How a combination of radical clock experiments and in situ photoNMR spectroscopy revealed the identities of the key radical species and the putative aryl dioxazolidine intermediates, respectively.Watched the video and ready to learn more?

Development of New Synthetic Methodologies Enabled by Advion Interchim Scientific Workflow

Recorded May 5, 2022.

Join Daniel Kim, Ph.D., Assistant Professor ​Organic, Inorganic, Biological, from Temple University, as he presents several new methodologies developed for reaction discovery.

In this webinar, you will learn:

  • How to develop a fast and modular workflow for reaction discovery on a budget
  • The advantages to using Advion-Interchim Scientific suite of instruments
  • A review of unpublished work on developing new reaction discovery

Streamlined Benchtop Chemistry: Faster Workflow from Reaction to Fraction

Lab Manager Ask the Expert Webinar. Recorded September 7, 2022

Maximize your workflow—even with limited space at the bench. This webinar features innovative solutions for streamlining the chemists’ everyday needs, including reaction monitoring, purification, fraction collection, and evaporation. No matter what your application, the session will address some of the most common bottlenecks and how to avoid them to improve your process.

As a viewer, you will learn more about:

  • How to use TLC plates to make flash purification faster and more efficient
  • Software hacks leveraging sophisticated algorithms for better purifications
  • 30-second fraction ID to speed up the process
  • How evaporation can be easier, faster, and more reliable

Webinar speakers include:

Gary Williams
Vice President, Chemist & North American Sales
Advion Interchim Scientific

Nathaniel Kunzer
Product Specialist
Heidolph

Continuous Purification from Flow Chemistry Systems with In-Line Flash Chromatography

Recorded June 15, 2022.

Join Christopher Thomson, Researcher at Heriot-Watt University, as he shares his work expanding the tool kit of automated flow synthesis with the development of in-line flash chromatography purification.

In this webinar, you will learn:

  • An introduction to flow chemistry and in-line purification technologies.
  • An overview of prior continuous chromatography methods, their advantages and limitations.
  • How to interface flow reactors with puriFlash automated chromatography systems.
  • ‘Tips & Tricks’ for performing continuous in-line flash chromatography.
  • Future prospects for developing in-line flash chromatography.

Chris completed his chemistry with biochemistry degree (MChem, 1st Class) at Heriot-Watt University, Edinburgh, in 2018 and was recipient of the ‘William H. Perkin Prize’ for excellence in organic chemistry. He was then awarded a PhD scholarship through the EPSRC funded centre for doctoral training in critical resource catalysis (CRITICAT), under the joint supervision of Dr Filipe Vilela and Dr Ai-Lan Lee.

Chris’ research focuses on the development and implementation of enabling technologies – especially flow chemistry – to enhance heterogeneous photocatalysis for organic synthesis.

He has published several papers on the development of flow systems featuring enabling technologies, such as: in-line NMR spectroscopy, in-line UV-Vis. spectroscopy, static mixing photocatalyst monoliths produced via functional material additive manufacturing, and most recently, reported the first example of continuous in-line flash chromatography – which will be the subject of this webinar.

Complement Flow Synthesis With In-Line Purification Using Flash Chromatography

In this application note, we describe a novel method to perform the continuous isolation of flow synthesis products from residual starting materials, catalysts or by-products to expedite chemical discovery. A promising new approach is highlighted here, featuring the Advion Interchim Scientific puriFlash® 5.250 preparative LC system.

The first results of our cooperation with the VilelaLAB and Continuum Flow Lab at Heriot-Watt University, Edinburgh, on this topic are outlined here and can be read in more detail in the following source: C.G.Thomson et al.: Expanding the Tool Kit of Automated Flow Synthesis: Development of In-line Flash Chromatography Purification, J. Org. Chem. 2021, 86, 20, 14079–14094.

Setting Up Flash Chromatography in Your Lab: Faster Workflows for Better Purifications

Avoid workflow bottlenecks by streamlining the flash purification process in your lab. This whitepaper can help you identify, reduce, or even eliminate these bottlenecks, tanking your standard operational time from hours to minutes. Learn how essential tools including TLC, a smartphone application and a simple dipping probe for fraction ID offer a novel, systematic approach to help accelerate both synthesis and purification.

Key Objectives:
  • Learn the key tools to setting up a streamlined purification workflow in your lab.
  • Review the most time-consuming processes in a routine flash purification workflow and how to avoid these bottlenecks.
  • Explore how modern technology, including a smartphone application, can assist with method development.

puriFlash® XS-Vap

The NEW puriFlash® XS-Vap, your intuitive laboratory evaporator. X-tra compact. X-tra intuitive. X-tra efficient. X-tra evaporation.

Reduce evaporation time and gas consumption with the most advanced evaporator on the market. The puriFlash® XS-Vap offers an extensive range of benefits over the competition:

  • Compact and robust
  • Dedicated to solvent evaporation & concentration
  • Up to 90 samples in parallel
  • From 1mL to 250mL per position
  • Low gas consumption due to nozzle adjustment
  • Integrated software
  • Compatible with puriFlash racks