Prep scale SFC/CMS Interface – passive split

Supercritical fluid chromatography (SFC) is a fast growing technique. Initially used almost exclusively for only thermally labile and chiral compounds it is now becoming accepted as a versatile analytical technique applied across a broad range of compounds. It is faster and higher-throughput than regular HPLC and Preparative LC and becoming popular as a ‘green’ technique, with far lower solvent consumption and lower consumable cost than HPLC. SFC is also compatible with a wide range of detection methods including electrospray (ESI) and atmospheric pressure chemical ionization (APCI) mass spectrometry.

Download this product note to see how SFC combined with compact mass spectrometry (CMS) offers chemists several benefits.