Monitoring Synthetic Reactions Using an (inert) Atmospheric Solids Analysis Probe (iASAP)
Metal based compounds have found utility in various fields such as clinical, energy, food safety and environmental to name a few. Creating the metal complex is the last step in a synthetic process when ligands are bound to the metal center. Once made, these metal complexes can be used anywhere from stereospecific synthesis to anti-cancer drugs. It is critical that reaction conditions are providing the desired product and that side products are kept to a minimum to maximize yield. Presented here is the use of an inert atmospheric solid analysis (iASAP) probe to quickly sample and measure the reaction via mass spectrometry.