Department of Chemistry – Creighton University
Q: WHAT IS THE FOCUS OF YOUR LAB’S RESEARCH?
A: The synthesis of modified histidines for solid-phase peptide synthesis and new routes to exocyclic allenes.
Q: WHATE WAS YOUR PREVIOUS WORK FLOW OR CHALLENGE?
A: Some Nim-tritylated histidine analogues and exocyclic allenes provided weak or no molecular ions using other mass spectrometry methods.
Q: WHY DID YOU INCORPORATE THE EXPRESSION CMS INTO YOUR LABORATORY?
A: It’s easy, walk-up use with straightforward swapping of ESI and APCI sources make it a reliable, productive tool for determining synthetic success.
Q: HOW DID THE EXPRESSION CMS HELP RESOLVE YOUR CHALLENGES?
A: ESI and APCI resolved extensive fragmentation observed with some analytes.
Q: TO WHOM WOULD YOU RECOMMEND THE EXPRESSION CMS?
A: Organic synthesis labs and undergraduate programs needing a simple diagnostic tool for reaction outcomes.
Q: WHAT IMPRESSES YOU THE MOST ABOUT THE EXPRESSION CMS?
A: Students find it straightforward to use and its sources are easy to clean.