Plate Express®: How it Works

Advion Interchim Scientific’s Plate Express® is ideal for fast, easy TLC/MS analysis. Coupled with the expression® Compact Mass Spectrometer (CMS), the TLC plate reader allows prep-free sampling and data in less than 30 seconds.

ASAP®: How it Works

Advion’s direct atmospheric solids analysis probe, otherwise known as ASAP®, permits chemists fast and reliable sample analysis of liquid and solid samples such as reaction mixtures, food samples, natural products and tablets.

Mobile Mass Spectrometry: Taking the Laboratory to the Field – Featuring Research by the University of Sheffield

In this webinar, Heather Walker from Sheffield University’s plant production and protection team explains how taking a compact mass spectrometer from the lab to the field helped optimise the team’s research.

The webinar highlights the advantages of mobile mass spectrometry, and introduces a mobile mass spec vehicle that has been outfitted to optimize time in the field without sacrificing results for real-time decision making about sampling.

During this webinar you will learn:

  • about fast and easy sample techniques available with compact mass spectrometry, including direct probe for liquids and solids, and a volatile headspace analysis tool – both with no sample preparation required
  • how instant data can be obtained to provide real-time decision making, allowing for smaller sample sizes to optimise reproducibility – without the need to oversample with the intent of bringing samples for off-site lab testing
  • how the metabolic profile of wheat can be measured via compact mass spectrometry, highlighting the success of the technology in the food and ingredients testing industry

This webinar is brought in association with Advion and will feature presentations from Advion’s scientific founder Jack Henion and Sheffield University’s Heather Walker.

Food and Ingredients Analysis

Integrated Solutions for Food Authenticity, Characterization and Safety with the expression® Compact Mass Spectrometer, AVANT® (U)HPLC and SOLATION® ICP-MS 

Your integrated laboratory solution for comprehensive testing of food, ingredients and natural products. Advion offers a full suite of analytical instrumentation for characterization, screening and purity determination, including:

  • expression® CMS – The expression® Compact Mass Spectrometer (CMS) offers the industry’s widest range of sample introduction systems, providing rapid answers with little or no sample prep in < 30 seconds.
  • SOLATION® ICP-MS – Provides fast, simple, multi-element analysis of toxic metals, and essential elements and minerals in a wide array of samples, including water, soil, plant material, food and raw ingredients 
  • AVANT® HPLC & UHPLC – Advion’s range of modular high performance, liquid chromatography systems can be used standalone with UV and UV/Vis detector options, or with the expression® CMS to provide seamlessly integrated LC/CMS under the full control of Advion’s simple, intuitive software suite. 
  • PLATE EXPRESS® TLC PLATE READER – Plate Express® provides a simple, automated means of obtaining mass spectra directly from TLC plates, combined with Advion’s expression® CMS creating a technique known as TLC/ CMS. See results in < 30 seconds at the push of a button. 

ASAP® Atmospheric Solids Analysis Probe

For Direct Mass Analysis of Liquid & Solid Samples with the expression® CMS

The direct atmospheric solids analysis probe, otherwise known as ASAP®, permits chemists fast and reliable sample analysis of liquid and solid samples such as reaction mixtures, food samples, natural products and tablets.

Chemists simply dip the closed end of a glass capillary into the sample of interest (even complex mixtures) or scrape the surface of a solid, and then place the capillary into the CMS for analysis.

Clean-up and analysis is a single step. Involatile buffers and salts remain on the capillary ensuring they do not suppress ionization or interfere with the measurement, while the compounds of interest are identified by the CMS.

In addition, users benefit from solvent-free APCI, which ionizes a wider range of compounds.

Plate Express®: Direct Mass Analysis from TLC Plates

Provides simple, automated MS analysis in seconds, directly from TLC plates

The Plate Express® is a device that provides a simple, automated means of obtaining mass spectra directly from TLC plates, creating a technique known as TLC/MS. Combined with Advion Interchim Scientific’s expression® compact mass spectrometer (CMS) this becomes TLC/CMS. Using this technique, chemists can quickly and confidently identify products even in complex mixtures without additional sample preparation.

  • Identify spots in <1 minute
  • Avoid the risk of overloading the mass spectrometer – TLC spots contain the ideal amount of sample for mass spectrometry
  • Software controlled – spectra obtained within a few mouse clicks
  • Simplify the process of obtaining spectra – ideal for multi-user labs

iASAP Inert Atmospheric Solids Analysis Probe

For Direct Mass Analysis of Air-Sensitive Samples, Catalysts and Organometallics at the Bench With the expression® CMS

The Atmospheric Solids Analysis Probe (ASAP®) allows chemists to directly analyze liquid and solid samples by mass spectrometer without the need for sample preparation at the bench, right next to the reaction. The inert ASAP (iASAP) is a modification of this technique, allowing easy sampling of air-sensitive compounds, such as metal catalysts and organometallics, from reactions that are carried out in a glove box or Schlenk line to prevent oxidation.

The technique allows a synthetic chemist to perform real-time reaction monitoring by sampling the compound with the special iASAP probe, which is designed to provide access to a sample protected in a glovebox or Schlenk line, then transferring the sample to the CMS, while continuing to protect it in an inert environment where it is ionized by atmospheric pressure chemical ionization (APCI). Mass Spectra are acquired in seconds.

AVANT® HPLC & (U)HPLC Chromatography Systems

Providing simple, high-performance, LC/CMS with the expression® CMS

Modular, stackable design, with many options provides custom solutions for both HPLC and UHPLC needs. From the simplest manual injection HPLC to a fully automated, streamlined UHPLC system and everything in-between, the Avant series can be configured to fit your analytical requirements and your budget.

The AVANT® (U)HPLC series is the latest in Advion’s innovative line of sample inlet devices for the expression® CMS which include:

  • Plate Express® for automated mass assays from TLC plates
  • The ASAP® direct analysis probe for solid, liquid and even air sensitive samples using iASAP
  • vAPCI for analysis of volatile organic compounds (VOCs) from head spaces, breath, and other gas samples.
  • Flow chemistry interfaces

All these techniques can be simply, simultaneously, interfaced with the CMS so that the chemist can move quickly and effortlessly between workflows.

Touch Express Open Port Sampling Interface

For One-Touch Mass Analysis of Solids, Liquids, Surfaces and Fibers with the expression® CMS 

The Touch Express Open Port Sampling Interface (OPSI), is designed for simple sampling of surfaces, solids, liquids and sample preparation tips and fibers. The novel ambient sampling technique was developed by Gary Van Berkel and Vilmos Kertesz, of Oak Ridge National Laboratory. 

Paired with the electrospray ion source of the expression® Compact Mass Spectrometer, the solvent forms a meniscus at the open port before being drawn down the inner path into the electrospray ion source of the mass spectrometer under the Venturi effect of the nebulization gas. Any soluble sample touching the port is analyzed by the mass spectrometer in just seconds. Touch Express OPSI offers a fast assay bench-top solution for solid, liquids, and surfaces in a small-footprint, easy-to-use system. 

SOLATION® ICP-MS

Introducing the new SOLATION® Inductively Coupled Plasma Mass Spectrometer (ICP-MS) – the ultimate instrument for multi-element analysis, the SOLATION® provides high sensitivity measurement of trace elements from a wide range of matrices including complex samples such as urine, serum, plasma, whole blood and tissue samples. Designed for ease of use, with intuitive software, the SOLATION® ICP-MS is the ideal instrument for environmental, pharmaceutical, food safety and clinical laboratories everywhere.

Fill out the form to download the full SOLATION® ICP-MS brochure now.