For Direct Mass Analysis of Liquid & Solid Samples with the expression® CMS
The direct atmospheric solids analysis probe, otherwise known as ASAP®, permits chemists fast and reliable sample analysis of liquid and solid samples such as reaction mixtures, food samples, natural products and tablets.
Chemists simply dip the closed end of a glass capillary into the sample of interest (even complex mixtures) or scrape the surface of a solid, and then place the capillary into the CMS for analysis.
Clean-up and analysis is a single step. Involatile buffers and salts remain on the capillary ensuring they do not suppress ionization or interfere with the measurement, while the compounds of interest are identified by the CMS.
In addition, users benefit from solvent-free APCI, which ionizes a wider range of compounds.
Provides simple, automated MS analysis in seconds, directly from TLC plates
The Plate Express® is a device that provides a simple, automated means of obtaining mass spectra directly from TLC plates, creating a technique known as TLC/MS. Combined with Advion Interchim Scientific’s expression® compact mass spectrometer (CMS) this becomes TLC/CMS. Using this technique, chemists can quickly and confidently identify products even in complex mixtures without additional sample preparation.
- Identify spots in <1 minute
- Avoid the risk of overloading the mass spectrometer – TLC spots contain the ideal amount of sample for mass spectrometry
- Software controlled – spectra obtained within a few mouse clicks
- Simplify the process of obtaining spectra – ideal for multi-user labs
Providing simple, high-performance, LC/CMS with the expression® CMS
Modular, stackable design, with many options provides custom solutions for both HPLC and UHPLC needs. From the simplest manual injection HPLC to a fully automated, streamlined UHPLC system and everything in-between, the Avant series can be configured to fit your analytical requirements and your budget.
The AVANT® (U)HPLC series is the latest in Advion’s innovative line of sample inlet devices for the expression® CMS which include:
- Plate Express® for automated mass assays from TLC plates
- The ASAP® direct analysis probe for solid, liquid and even air sensitive samples using iASAP
- vAPCI for analysis of volatile organic compounds (VOCs) from head spaces, breath, and other gas samples.
- Flow chemistry interfaces
All these techniques can be simply, simultaneously, interfaced with the CMS so that the chemist can move quickly and effortlessly between workflows.
For One-Touch Mass Analysis of Solids, Liquids, Surfaces and Fibers with the expression® CMS
The Touch Express™ Open Port Sampling Interface (OPSI), is designed for simple sampling of surfaces, solids, liquids and sample preparation tips and fibers. The novel ambient sampling technique was developed by Gary Van Berkel and Vilmos Kertesz, of Oak Ridge National Laboratory.
Paired with the electrospray ion source of the expression® Compact Mass Spectrometer, the solvent forms a meniscus at the open port before being drawn down the inner path into the electrospray ion source of the mass spectrometer under the Venturi effect of the nebulization gas. Any soluble sample touching the port is analyzed by the mass spectrometer in just seconds. Touch Express™ OPSI offers a fast assay bench-top solution for solid, liquids, and surfaces in a small-footprint, easy-to-use system.
Overview
A simple, sensitive and selective ASAP® sample introduction approach to measuring the presence of two isobaric compounds, CBDA and THCA, contained in a complex sample such as hemp or cannabis plants or their corresponding extraction products. Measurements are made of differences in the relative composition of CBDA and THCA fragment ions originating from the same precursor ion. Applicability to screening plants and plant product materials such as hemp or marijuana to monitor out-of-specification composition is demonstrated.
This poster was presented at the 2018 Cannabis Science Conference in Portland, OR.
Introducing the new SOLATION® Inductively Coupled Plasma Mass Spectrometer (ICP-MS) – the ultimate instrument for multi-element analysis, the SOLATION® provides high sensitivity measurement of trace elements from a wide range of matrices including complex samples such as urine, serum, plasma, whole blood and tissue samples. Designed for ease of use, with intuitive software, the SOLATION® ICP-MS is the ideal instrument for environmental, pharmaceutical, food safety and clinical laboratories everywhere.
Fill out the form to download the full SOLATION® ICP-MS brochure now.
Introduction
The legalization of marijuana and hemp provides commercial opportunities as well as analytical challenges. Accurate and precise quantitative analysis of plant and medicinal products is needed in this new industry to document composition and assure the safety of cannabis products. LC/MS techniques can provide unparalleled selective and sensitive measurements for these purposes. Here we describe the use of a relatively inexpensive compact mass spectrometer for SIM LC/MS analysis of cannabis-related applications.
This poster was presented at ASMS 2018 Annual Conference in San Diego, CA.
Advion Interchim Scientific’s range of AVANT®, high performance, liquid chromatography systems can be used standalone with UV and UV/Vis detector options, or with the expression® compact mass spectrometer to provide seamlessly integrated LC/CMS under the full control of Advion Interchim Scientific’s simple, intuitive Mass Express software suite.
Modular, stackable design, with many options, provides custom solutions for both HPLC and UHPLC needs. From the simplest manual injection HPLC to a fully automated, streamlined UHPLC system and everything in-between, the AVANT® series can be configured to fit your analytical requirements and your budget.
Quant Express, an addition to Advion’s user-friendly Mass Express 4.0 software suite, features quantitation to create a fully integrated software system for expression CMS users.
Introducing a new type of mass spectrum, available exclusively in the Advion Peak Express™ software suite: the Delta Spectrum (ΔS). The ΔS is available with the expression compact mass spectrometer (CMS) to look beyond chemical noise and automatically detect even the smallest peaks without knowing the m/z in advance.
With the Peak Express™ software, you can:
- Find minor components and impurities you would otherwise miss
- Find unknowns in complex samples like natural products
- Acquire XIC-quality data while scanning the entire mass range, allowing Peak Express™ to tell you the m/z
- Perform real-time, mass-directed purification without knowing the mass Realize automatic ‘expert’ data processing
