Mass Directed Fraction Collection by Reverse Phase Flash Chromatography Coupled to the expression CMS

In this application note, we compare the use of a flash chromatography system with a UV detector alone versus the same system paired with a mass spectrometer. The data highlights the impact on workflow efficiency and underscores the importance of selecting the appropriate splitter.

The specificity of MS detection improves the efficiency of the purification workflow (compared to traditional Flash and HPLC).