expression CMS

High performance compact mass spectrometer

The expression CMS provides essential information quickly and improves the chemist’s workflow. Modern organic labs have become automated; faster and more critical reactions require co-located versatile analytics — the expression CMS solves this at an affordable price.

"Our laboratory has recently purchased an Advion expression Compact Mass Spectrometer. Our choice was not only related to the small footprint but also to the versatility of the system. The Advion expression CMS provides the quality of results necessary to improve research outcomes in our hit and lead discovery efforts."

Tiago Rodrigues – ETH Zürich, Switzerland

Versatility

Few laboratories analyze one type of sample or one technique all day, every day. Most require the ability to analyze a range of samples using more than one technique. This allows for a more complete identification and characterization of samples. The expression CMS integrates with nearly every chemistry technique.

  • Atmospheric Solids Analysis Probe (ASAP)
  • Thin-layer Chromatography (TLC by Plate Express)
  • 'Tides (peptide and other biomolecule analysis system)
  • Flow Injection
  • UHPLC
  • Flow Chemistry
  • Flash Chromatography
  • Preparative Liquid Chromatography (Prep-LC)
  • Supercritical Fluids Chromatography (SFC)

VIDEO: How to Perform Easy & Rapid Compound ID

"My recent initiative in providing and finding research funding has resulted in the purchase of the first Advion expression compact mass spectrometer to be installed in Australia in our research laboratory. This will improve the quality of the decision making process of my PG students in the research place leading to more efficient research outcomes and provide a mass spectral service to disciplines in our college at RMIT University." Helmut Hugel - RMIT University, Australia

expression CMS Success Stories

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Mass Spectrometry Facility, Department of Chemistry University of Birmingham

“The Chemists are spending significantly more time running reactions.”

Chi Tsang, Experimental Officer

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Technical University Munich, Garching, Germany

“The expression CMS is the perfect MS system for any research laboratory involved in synthetic organic chemistry and chemical analytics or small molecules to proteins.”

Dr. Tobias A.M. Gulder, Professor

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New Path Molecular Ltd, United Kingdom

“expression CMS meets our requirements for an instrument that is intuitive to use, robust and capable of being maintained, expanded and serviced without manufacturer call outs.”

Dr. Gary Tarver, Lead Chemist

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Corden Pharma Switzerland LLC, Liestal, Switzerland

"We use the Advion expression CMS as a robust and versatile detector in our chromatographic processes, both MPLC and HPLC."

Dr. Markus Juza, Purification Expert

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Recent expression CMS Publications

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expression CMS Application Notes

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Direct Analysis of Intact Proteins using the Advion Touch Express© Open Port Sampling Interface (OPSI) with the expressionL Compact Mass Spectrometer

Touch ExpressTM is a new sampling device for mass spec analysis using a technique developed by Gary Van Berkel and Vilmos Kertesz of Oak Ridge National Laboratory – the Open Port Sample Interface (OPSI). This fast, versatile sample inlet paired with the expression Compact Mass Spectrometer (CMS) provides simple molecular weight determination of surfaces, solids and liquids in < 30s.

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Fast Identification of Artificial Vanilla Flavor in Vanilla Extract by ASAP® Compact Mass Spectrometry

The expression CMS coupled with the Atmospheric Solids Analysis Probe (ASAP®) is used to quickly identify the presence of artificial vanilla, as well as confirm the purity of products marketed as such. This technique provides a fast and easy method for purity analysis.

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Fast Screening for Purity and Adulterants in Coconut Oil by ASAP® Compact Mass Spectrometry

The expression CMS coupled with the Atmospheric Solids Analysis Probe (ASAP®) is used to determine purity and detect adulterants in coconut oil. In this application note, pure coconut oil is tested against a sample of coconut oil adulterated with canola oil for comparative data analysis and a fast and easy method for purity analysis.

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iASAP Analysis of Air-Sensitive Compounds via Inert Sampling Techniques

Many chemical reactions carried out by synthetic chemists involve air-sensitive compounds such as metal catalysts and organometallics and must therefore be carried out in a glove box or using a Schlenk line to prevent oxidation and hydrolysis. Sampling and transportation of these samples to a mass spectrometer by an Atmospheric Solids Analysis Probe (ASAP ®)…

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