Chemists are tasked with quickly identifying compounds created, ensuring quality of products or evaluating safety. Current techniques are adequate, but not all offer speed, data quality or ease-of-use provided by the expression Compact Mass Spectrometer (CMS). The expression CMS with the direct analysis probe (ASAP®) offers chemists the ability to rapidly analyze solids, liquids and powders without tedious and time consuming sample preparation.
Using the TriVersa NanoMate with LESA for Analyte Profiling in Material Science
Surface analysis techniques have gained significant attention over the last couple of years with LESA being an interesting alternative to techniques such as SIMS or MALDI imaging. A new application note demonstrates practical applications for LESA in the material sciences.
LC/MS Determination of Amino Acids Using Compact Mass Spectrometry
See examples for the determination of amino acids on a combined HPLC compact mass spectrometry (LC/CMS) system for the rapid detection and quantification of amino acids utilizing a novel mixed mode LC column.
“Essential for any Lipidomics Laboratory.”
Associate Professor Christer S. Ejsing at the University of Southern Denmark uses the TriVersa NanoMate, as an essential laboratory instrument, for the development and applications of Lipidomic technology.
New publication: Direct analysis of intact proteins from Escherichia coli colonies by LESA mass spectrometry
Researchers in the UK have demonstrated the use of Liquid Extraction Surface Analysis (LESA) on the TriVersa NanoMate for top-down identification of proteins directly from living bacterial colonies grown in Petri dishes, without sample preparation. The method offers “improved sampling precision and could be useful for spatial profiling of bacterial colonies or analysis of contaminated surfaces.”
New Video: Direct Analysis of Liquids and Solids
Direct sample analysis of liquids, solids and powders without chromatography is as easy as it sounds, and provides mass spectral information within seconds. Our new video demonstrates analysis of a reaction mixture.
Environmental Analysis: Quantitation of Perchlorate by Ion Chromatography with Supressed Conductivity on the expression CMS
The expression Compact Mass Spectrometer (CMS) provides lower detection limits and greater selectivity for Perchlorate compared to a conductivity detector (CD).
“Anyone interested in volatiles will find the CMS is an excellent instrument for targeted analysis.”
Dr. James Reynolds’s group at the University of Loughborough conducts analysis of volatiles by direct breath analysis. The expression CMS allows for highly sensitive dermination of volatile species in breath with no preconcentration.
Reaction Monitoring by Direct Analysis Probe on a Compact Mass Spectrometer
The expression CMS provides essential compound information quickly and improves the chemist’s workflow. The Atmospheric Solids Analysis Probe (ASAP) permits fast analysis of solid and liquid samples and is a simple, faster and lower cost alternative to LC/MS methods. This direct analysis probe method has been shown to be useful for the analysis of volatile and semivolatile compounds. ASAP is available as a combined ASAP-APCI source, or existing APCI sources can be easily modified to become dual APCI-ASAP capable.
“Everyone can use it, including students.”
Dr. Frédéric Schmidt’s group at the Institut Curie in Paris had previously given their samples to outside MS services for analysis and had to wait for the results. Incorporating Advion’s expression CMS into their lab allowed them to have a self-service option that everyone could use. And the new workflow sped up their process significantly.