Creighton University, Department of Chemistry

Q: WHAT IS THE FOCUS OF YOUR LAB’S RESEARCH?
A: The synthesis of modified histidines for solid-phase peptide synthesis and new routes to exocyclic allenes.

Q: WHAT WAS YOUR PREVIOUS WORK FLOW OR CHALLENGE?

A: Some Nim-tritylated histidine analogues and exocyclic allenes provided weak or no molecular ions using other mass spectrometry methods.

Q: WHY DID YOU INCORPORATE THE EXPRESSION^® CMS INTO YOUR LABORATORY?

A: It’s easy, walk-up use with straight-forward swapping of ESI and APCI sources make it a reliable, productive tool for determining synthetic success.

Q: HOW DID THE EXPRESSION^® CMS HELP RESOLVE YOUR CHALLENGES?

A: ESI and APCI resolved extensive fragmentation observed with some analytes.

Q: TO WHOM WOULD YOU RECOMMEND THE EXPRESSION^® CMS?

A: Organic synthesis labs and undergraduate programs needing a simple diagnostic tool for reaction outcomes.

Q: WHAT IMPRESSES YOU THE MOST ABOUT THE EXPRESSION^® CMS?

A: Students find it straight-forward to use and its sources are easy to clean.