Compact mass spectrometry in modern SPPS

Specialty Chemicals Magazine March 2016

Mass spectrometry (MS) has been shown to be a very powerful analysis tool for peptides and proteins and is routinely used in proteomics and in antibody and small molecule synthesis applications. MS can provide not only the molecular mass information of the SPPS cycle product but also AA sequence and structural information through specific and selective molecule fragmentation along the AA backbone.

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