"We can now analyse highly air sensitive compounds without difficulty and outside a glove box."

Success Story

Albert-Ludwigs-University, Freiburg, Germany

Prof. Dr. Ingo Krossing
Institute for Inorganic and Analytical Chemistry
Q: WHAT IS THE FOCUS OF YOUR LAB’S RESEARCH?

A: We investigate ionic systems to the fullest extent, both experimentally and theoretically. In doing so, we want to understand and exploit the fundamental principles that determine the behaviour of such systems.

Q: WHAT WAS YOUR PREVIOUS WORK FLOW OR CHALLENGES?

A: For sample analysis we use NMR, vibrational Spectroscopy and X-Ray Diffraction along with electrochemical measurements in our laboratory. However, for mass spectra the samples had to be given to the MS service of the chemistry department. This led to noticeable waiting times, so no reaction monitoring was possible. Also, some of the compounds usually lead to large memory effects and are therefore rather ‘unpopular’ at the MS service. Furthermore, a large part of the compounds we synthesize are air sensitive and could not be measured at all.

Q: WHY DID YOU INCORPORATE THE EXPRESSION CMS INTO YOUR LABORATORY?

A: With the expression CMS in our laboratory we can now use mass spectrometry as standard analysis tool for reaction monitoring. PhD Students can measure their own samples directly after synthesis. They can even change the ion source on their own according to the nature of their samples. Samples with large memory effect are no longer problematic, as the inlet capillary can easily be cleaned. A major advantage is that we can now analyse highly air sensitive compounds without difficulty and outside a glove box.

Q: WHO WOULD YOU RECOMMEND TO PURCHASE THE EXPRESSION CMS?

A: We would recommend the expression CMS to anyone who wants to implement MS as a fast and easy to operate standard method within their own lab.