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Purdue University

I was so impressed with the user-friendly interface and instrument setup that we installed a 4th expression CMS to be used in the undergraduate organic teaching lab.

Flaherty Lab

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Webinar featuring Advion Touch Express™ Open Port Sampling Interface (OPSI)

The Touch ExpressTM Open Port Sampling Interface (OPSI), is designed for simple sampling of solids, liquids and sample preparation tips and fibers. The novel ambient sampling technique was developed by Gary Van Berkel and Vilmos Kertesz, of Oak Ridge National Laboratory. Paired with the electrospray ion source of the expression Compact Mass Spectrometer, the product…

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Customer Profile

New Path Molecular Ltd, United Kingdom

“expression CMS meets our requirements for an instrument that is intuitive to use, robust and capable of being maintained, expanded and serviced without manufacturer call outs.”

Dr. Gary Tarver, Lead Chemist

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University of North Carolina, Biomedical Research Imaging Center (BRIC)

“The convenience of having a mass spectrometer in our laboratory means that we can increase working efficiencies.”

Dr. Zibo Li, Department of Radiology UNC School of Medicine

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University of Ljubljana, Slovenia

"We recommend this to every medicinal chemistry department."

Dr. Janez Ilaš, Associate Professor, The Chair of Pharmaceutical Chemistry, Faculty of Pharmacy

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University of Hull, Chemistry Department

"A cost effective way to introduce practical LCMS studies to the undergraduate laboratory class."

Kevin Welham, Department of Chemistry

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University of North Carolina at Pembroke, Department of Chemistry and Physics

"Well suited for a variety of undergraduate curricular and research lab applications."

Paul Anthony Flowers, Professor of Chemistry

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Liverpool School of Tropical Medicine (LSTM), United Kingdom

"You do not need to be an expert in mass spectrometry to generate very useful and meaningful data."

Sitthivut Charoensutthivarakul

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University of Hull, Archibald Group

"The expression CMS has undoubtedly saved our group a great deal of time and has advanced our research."

Rhiannon Lee, Ph.D., Department of Chemistry and Positron Emission Tomography Research Centre

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University of Dundee, Drug Discovery Unit (DDU), United Kingdom

"Easy to install, operate, and move."

Margaret Huggett, Medicinal Chemist, Drug Discovery Unit

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SynZeal Research Pvt Ltd, Ahmedabad, Gujarat, India

"I recommend expression CMS as an affordable alternative for mass analysis."

Dr. Jitendra Kaila, PhD, Director

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expression CMS: Compact. Fast. Easy. & Affordable

With over 20 years of mass spectrometry and chemistry expertise, Advion has produced a family of compact mass spectrometers designed for the chemist. The affordability, small size and ease of use make them ideal for use directly at the chemist’s bench, giving immediate answers and informed decisions instead of waiting. The Advion expression compact mass…

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University of Loughborough, Centre for Analytical Sciences

"Anyone interested in volatiles will find the CMS is an excellent instrument for targeted analysis."

James Reynolds, PhD, Research Scientist

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Reach Separations, United Kingdom

"The expression CMS is an excellent all round instrument that meets our needs perfectly"

Peter Ridgway, Business Development Director

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Boston College, Center for Mass Spectrometry (CMS)

"I would highly recommend the purchase of the expression CMS, especially to core labs or any small college looking for a well-made easy to use system."

Marek A. Domin MSc, MRSC, CChem, CSci, Director of Mass Spectrometry

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Institut Curie, France

"Everyone can use it, including students."

Frédéric Schmidt, PhD, Senior Scientist, Group Leader

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Electrospray LC/MS response differences from equimolar quantities of drugs using a compact mass spectrometer equipped with atmospheric pressure ionization

The purpose of this study was to evaluate the positive and negative electrospray (ESI) and atmospheric pressure chemical ionization (APCI) LC/MS ion current response from a representative synthetic mixture of standard pharmaceutical compounds. The selected drup compounds were prepared as an equimolar mixture and analyzed by an optimized gradient LC/MS procedure using a novel compact…

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Montclair State University, Rotella Lab

"The expression CMS is easily serviceable by a non-expert."

David Rotella, PhD, Professor, Chemistry & Biochemistry

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Virginia Tech, Matson Research Group

"There is no substitute for having a mass spectrometer a few steps away from your bench."

John Matson, PhD, Assistant Professor

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Application Note

Simple, high-performance coupling of SFC to CMS for mass-directed fraction collection

Recently, Advion co-authored with a major pharmaceutical partner to create two application notes highlighting the benefits of supercritical fluid chromatography (SFC) coupled to a compact mass spectrometer for mass directed fraction collection.  The application notes conclude that mass‐directed fraction collection with a simplified passive splitter on the Preparative JASCO SFC coupled with expression CMS system…

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Real-Time monitoring of a Suzuki reaction utilizing a hood-based compact mass spectrometer

A novel compact single quadrupole mass spectrometer for hood-based applications in the analysis of chemical reactions. Medical chemists are routinely faced with personally over a hundred new chemical entities (NCE’s) each year for testing as future pharmaceutical drug candidates. The goal is to prepare a high yield, relatively pure product via an optimized synthetic route.

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