TriVersa NanoMate Select References

The TriVersa NanoMate is a valuable tool for many scientific research applications as follows:

Click on the publications titles to be redirected to the Pub Med abstract.

Click on “Journal Abstract” or “Article” to be redirected to the abstract or article on the publishing Journals’ websites.

LESA – Liquid Extraction Surface Analysis

(Click here to return to application menu)

Using a single, high mass resolution mass spectrometry platform to investigate ion suppression effects observed during tissue imaging L. Tomlinson; J. Fuchser; A. Futterer; M. Baumert; D.G. Hassall; A. West; P.S. Marshall Rapid Commun. Mass Spectrom. 2014, 28, 995-1003

Liquid Extraction Surface Analysis (LESA) of Hydrophobic TLC Plates Coupled to Chip-Based Nanoelectrospray High-resolution Mass Spectrometry  M. Himmelsbach; E. Varesio; G. Hopfgartner CHIMIA 2014, 68, Nr. 3 doi:10.2533/chimia.2014.150

Direct detection of brominated flame retardants from plastic e-waste using liquid extraction surface analysis mass spectrometry M.R.L. Paine, I.D. Rae, S.J. Blanksby  Rapid Commun. Mass Spectrom. 2014, 28, 1203-1208

Fully automated laser ablation liquid capture surface analysis using nanoelectrospray ionization mass spectrometry  M. Lorenz; O.S. Ovchinnikova; G.J. Van Berkel Rapid Commun. Mass Spectrom. 2014, 28, 1-9

Dried blood spot proteomics: surface extraction of endogenous proteins coupled with automated sample preparation and mass spectrometry analysis Martin NJ, Bunch J, Cooper HJ J Am Soc Mass Spectrom. 2013 Aug;24(8):1242-9

Microproteomics by liquid extraction surface analysis: Application to FFPE  tissue to study the fimbria region of tubo-ovarian cancer M. Wisztorski; B. Fatou; J. Franck; A. Desmons; I. Farre; E. Leblanc; I. Fournier; M. Salzet Proteomics Clin. Appl. 2013, 7, 1-7

Automated liquid microjunction surface sampling-HPLC-MS/MS analysis of drugs and metabolites in whole-body thin tissue section V. Kertesz; G.J. Van Berkel Bioanalysis 2013 Apr;5(7):819-26. doi: 10.4155/bio.13.42.

Direct Lipid Profiling of Single Cells from Inkjet Printed Microarrays
Ellis, S.R.; Ferris, C.J.; Gilmore, K.J.; Mitchell, T.W.; Blanksby, S.J.; In Het Panhuis, M.
Anal Chem. 2012 Nov 7. [Epub ahead of print]

Direct Surface Analysis of Time-Resolved Aerosol Impactor Samples with Ultrahigh-Resolution Mass Spectrometry
Fuller, S.J.; Zhao, Y.; Cliff, S.S.; Wexler, A.S.; Kalberer, M.
Anal Chem. 2012 Oct 30. [Epub ahead of print]

Top-down proteomics and direct surface sampling of neonatal dried blood spots: diagnosis of unknown hemoglobin variants
Edwards, R.L.; Griffiths, P.; Bunch, J.; Cooper, H.J.
J Am Soc Mass Spectrom. 2012 Nov;23(11):1921-30. doi: 10.1007/s13361-012-0477-9. Epub 2012 Sep 20.

Direct detection of additives and degradation products from polymers by liquid extraction surface analysis employing chip-based nanospray mass spectrometry
Paine, M. R. L.; Barker, P. J.; Maclauglin, S. A.; Mitchell, T. W.; Blanksby, S. J.
Rapid Commun Mass Spectrom. 2012 Feb 29;26(4):412-18. [Epub 2 012 Jan 15]

Utilizing the inherent electrolysis in a chip-based nanoelectrospray emitter system to facilitate selective ionization and mass spectrometric analysis of metallo alkylporphyrins
Van Berkel, G.J.; Vertesz, V.
Anal Bioanal Chem [Epub 2012 Jan 26] DOI 10.1007/s00216-011-5676-x

Investigation of figopitant and its metabolites in rat tissue by combining whole body autoradiography with liquid extraction surface analysis mass spectrometry
Schadt, S.; Kallback, S.; Almeida, R.; Sandel, J.
Drug Metab Dispos. [Epub 2011 Dec 19]. doi:10.1124/dmd.111.043562

Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example
Eikel, D.; Vavrek, M.; Smith, S.; Bason, C.; Yeh, S.; Korfmacher, W. A.; Henion, J. D.
Rapid Commun Mass Spectrom. 2011 Dec 15;25(23):3587-3596. [Epub 2011 Nov 16]

Direct sampling and analysis from solid-phase extraction cards using an automated liquid extraction surface analysis nanoelectrospray mass spectrometry system
Walworth, M.J.; ElNaggar, M.S.; Stankovich, J.J.; Witkowski, C.; Norris, J.L.; Van Berkel, G.J.
Rapid Commun Mass Spectrom. 2011 Sep 15;25(17):2389-96.
Journal Abstract

Liquid extraction surface analysis (LESA) of food surfaces employing chip-based nano-electrospray mass spectrometry
Eikel, D.; Henion, J.
Rapid Commun Mass Spectrom. 2011 Aug 30;25(16):2345-54. doi: 10.1002/rcm.5107

Utility of spatially-resolved atmospheric pressure surface sampling and ionization techniques as alternatives to mass spectrometric imaging (MSI) in drug metabolism
Blatherwick, E.Q.; Van Berkel, G.J.; Pickup, K.; Johansson, M.K.; Beaudoin, M.E.; Cole, R.O.; Day, J.M.; Iverson, S.; Wilson, I.D.; Scrivens, J.H., Weston, D.J.
Xenobiotica. 2011 Aug;41(8):720-34. [Epub 2011 Jun 14]
Journal Abstract

Comparative Lipidomics Profiling of Human Atherosclerotic Plaques
Stegemann, C.; Drozdov, I.; Shalhoub, J.; Humphries, J.; Ladroue, C.; Didangelos, A.; Baumert, M.; Allen, M.; Davies, A. H.; Monaco, C.; Smith, A.; Xu, Q.; Mayr, M.
Circ Cardiovasc Genet. 2011 Apr 21. [Epub ahead of print]

Hemoglobin Variant Analysis via Direct Surface Sampling of Dried Blood Spots Coupled with High-Resolution Mass Spectrometry
Edwards, R.L.; Creese, A.J.; Baumert, M.; Griffiths, P.; Bunch, J.; Cooper, H.J.
Anal Chem. 2010 Mar 15;83(6):2265-70. [Epub 2011 Feb 22]

Correlation of Skin Blanching and Percutaneous Absorption for Glucocorticoid Receptor Agonists by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging and Liquid Extraction Surface Analysis with Nanoelectrospray Ionization Mass Spectrometry
Marshall, P.; Toteu-Djomte, V.; Bareille, P.; Perry, H.; Brown, G.; Baumert, M.; Biggadike, K.
Anal. Chem. 2010;82(18):7787-94. [Epub 17 Aug 2010]
Journal Abstract

Fully automated liquid extraction-based surface sampling and ionization using a chip-based robotic nanoelectrospray platform
Kertesz, V.; Van Berkel, G.J.
J Mass Spectrom. 2010 Mar.;45(3):252-60. [Epub 17 Dec 2009]
Journal Abstract

Lipids Analysis

(Click here to return to application menu)

Shotgun lipidomics on a LTQ Orbitrap mass spectrometer by successive switching between acquisition polarity modes
Schuhmann, K.; Almeida, R.; Baumert, M.; Herzog, R.; Bornstein, S.R.; Shevchenko, A.
J. Mass. Spectrom. 2012, 47, 96-104

Assessment of the Molecular Expression and Structure of Gangliosides in Brain Metastasis of Lung Adenocarcinoma by an Advanced Approach Based on Fully Automated Chip-Nanoelectrospray Mass Spectrometry
Zamfir, A. D.; Serb, A.; Vukeli, Z.; Flangea, C.; Schioupu, C.; Fabris, D.; Kalanj-Bognar, S.; Capitan, F.; Sisu, E.
J Am Soc Mass Spectrom. 2011 Oct 15. [Epub ahead of print]
Journal Abstract

Reprint of: Chip-based nanoelectrospray mass spectrometry of brain gangliosides
Flangea, C.; Serb, A.; Sisu, E.; Zamfir, A.D.
Biochim Biophys Acta. 2011 Sep 18. [Epub ahead of print]
Journal Abstract

Comparative Lipidomics Profiling of Human Atherosclerotic Plaques
Stegemann, C.; Drozdov, I.; Shalhoub, J.; Humphries, J.; Ladroue, C.; Didangelos, A.; Baumert, M.; Allen, M.; Davies, AH.; Monaco, C.; Smith, A.; Xu, Q.; Mayr, M.
Circ Cardiovasc Genet. 2011 Apr 21. [Epub ahead of print]

Increase of oxidant-related triglycerides and phosphatidylcholines in serum and small intestinal mucosa during development of intestinal polyp formation in Min mice
Ikeda, K.; Mutoh, M.; Teraoka, N.; Nakanishi, H.; Wakabayashi, K.; Taguchi, R.
Cancer Sci. 2011 Jan.;102(1):79-87 [Epub 2010 Oct 14]

Orm family proteins mediate sphingolipid homeostasis Breslow, D.K.; Collins, S.R.; Bodenmiller, B.; Aebersold, R.; Simons, K.; Shevchenko, A.; Ejsing, C.S.; Weissman, J.S.
Nature. 2010 Feb 25;463(7284):1048-53.
Journal Abstract

Determination of ganglioside composition and structure in human brain hemangioma by chip-based nanoelectrospray ionization tandem mass spectrometry
Schiopu, C.; Flangea, C.; Capitan, F.; Serb, A.; Vukelić, Z.; Kalanj-Bognar, S.; Sisu, E.; Przybylski, M.; Zamfir, A.D.
Anal Bioanal Chem. 2009 Dec;395(8):2465-77. [Epub 2009 Oct 16]

High-throughput analysis of gangliosides in defined regions of fetal brain by fully automated chip-based nanoelectrospray ionization multi-stage mass spectrometry
Serb, A.; Schiopu, C.; Flangea, C.; Vukelić, Z.; Sisu, E.; Zagrean, L.; Zamfir, A. D.
Eur J Mass Spectrom. 2009;15(4):541-53.
Journal Abstract

Top-down glycolipidomics: fragmentation analysis of ganglioside oligosaccharide core and ceramide moiety by chip-nanoelectrospray collision-induced dissociation MS2-MS6
Serb, A.; Schiopu, C.; Flangea, C.; Sisu, E.; Zamfir, A. D.
J Mass Spectrom. 2009 Oct;44(10):1434-42.
Journal Abstract

A simple modification of a silicic acid lipid fractionation protocol to eliminate free fatty acids from glycolipid and phospholipid fractions
Dickson, L.; Bull, I.D.; Gates, P.J.; Evershed, R.P.
J Microbiol Methods. 2009 Sep;78(3):249-54. [Epub 2009 May 27]
Journal Abstract

Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network
Klemm, R.W.; Ejsing, C.S.; Surma, M.A.; Kaiser, H.-J.; Gerl, M.J.; Sampaio, J.L.; de Robillard, Q.; Ferguson, C.; Proszynski, T.J.; Shevchenko, A.; Simons, K.
J. Cell Biol . 2009 May 18;185(4):601-12. [Epub 2009 May 11]
Journal Abstract

High-throughput shotgun lipidomics by quadrupole time-of-flight mass spectrometry
Ståhlman, M.; Ejsing, C.S.; Tarasov, K.; Perman, J.;Borén, J.; Ekroos K.
J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Sep 15;877(26):2664-72. [Epub 2009 Feb 24]
Journal Abstract

Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry
Ejsing, C.S.; Sampaio, J.L.; Surendranath, V.; Duchoslav, E.; Ekroos, K.; Klemm, R.W.; Simons, K.; Shevchenko, A.
Proc Natl Acad Sci U.S.A. 2009 Feb 17;106(7):2136-41. [Epub 2009 Jan 27]

Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signaling
Zech, T.; Ejsing, C.S.; Gaus, K.; de Wet, B.; Shevchenko, A.; Simons, K.; Harder, T.
EMBO J. 2009, 28: 466–476.

Microfluidics-based electrospray ionization enhances the intrasource separation of lipid classes and extends identification of individual molecular species through multi-dimensional mass spectrometry: development of an automated high-throughput platform for shotgun lipidomics
Han, X.; Yang, K.; Gross, R.W. Rapid Commun Mass Spectrom. 2008 Jul;22(13):2115-24
Journal Abstract

Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics
Matyash, V.; Liebisch, G.; Kurzchalia, T.V.; Shevchenko, A.; Schwudke D.;
J. Lipid Res. 2008, 49: 1137-1146

Shotgun Lipidomics Identifies a Paired Rule for the Presence of Isomeric Ether Phospholipid Molecular Species
Yang, K.; Zhao, Z.; Gross, R. W.; Han, X.
PLoS ONE. 2007 ; 2(12): e1368

Top-Down Lipidomic Screens by Multivariate Analysis of High-Resolution Survey Mass Spectra
Schwudke, D.; Hannich, J.T.; Surendranath, V.; Grimard, V.; Moehring, T.; Burton , L.; Kurzchalia, T.; Shevchenko, A. Anal. Chem. 2007, Published on web.
Journal Abstract

Detection of the abundance of diacylglycerol and triacylglycerol molecular species in cells using neutral loss mass spectrometry
Murphy, R.C.; James, P.F.; McAnoy, A.M.; Krank, J.; Duchoslav, E.; Barkley, R.M.
Anal. BioChem. 2007 , 366:59-70

Osmolality, temperature and membrane lipid composition modulate the activity of betaine transporter BetP in Corynebacterium glutamicum

Özcan, N.; Ejsing, C.S.; Shevchenko, A.; Lipski, A.; Morbach, S.; Krämer, R.
J. Bacteriol. 2007 , 189(20): 7485-7496

Electrospray mass spectrometry of human hair wax esters
Fitzgerald, M.; Murphy, R.C.;
J. Lipid Res. 2007 , 48:1231–1246

FceRI and Thy-1 domains have unique protein and lipid compositions
Surviladze, Z.; Harrison, K.A.; Murphy, R.C.; Wilson, B.S.;
J. Lipid Res. 2007 , 48:1325–1335

Analysis of polyunsaturated aminophospholipid molecular species using isotope-tagged derivatives and tandem mass spectrometry/mass spectrometry/mass spectrometry
Zemski Berry , K.A.; Murphy, R.C.;
Anal. BioChem. 2006 , 349(1):118-128
Journal Abstract

Automated Identification and Quantification of Glycerophospholipid Molecular Species by Multiple Precursor Ion Scanning
Ejsing, C.S.; Duchoslav E.; Sampaio, J.; Simons, K.; Bonner, R.; Thiele, C.; Ekroos, K.; Shevchenko, A.
Anal. Chem. 2006 , 78(17):6202-14
Journal Abstract

Collision-induced dissociation pathways of yeast sphingolipids and their molecular profiling in total lipid extracts: a study by quadrupole TOF and linear ion trap–orbitrap mass spectrometry
Ejsing, C.S.; Moehring, T.; Bahr, U.; Duchoslav, E.; Karas, M.; Simons, K.; Shevchenko, A.
J. of Mass Spectrom. 2006 , 41:372-389
Journal Abstract

Lipid profiling by multiple precursor and neutral loss scanning driven by the data-dependent acquisition
Schwudke, D.; Oegema, J.; Burton, L.; Entchev, E.; Hannich, J.T.; Ejsing, C.S.; Kurzchalia, T.; Shevchenko,
A. Anal. Chem. 2006 , 78:585-595
Journal Abstract

Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation
Lindén, D.; William-Olsson, L.; Ahnmark, A.; Ekroos, K.; Hallberg, C.;Sjögren, H.P.; Becker, B.; Svensson, L; Clapham, J.C.; Oscarsson, J; Schreyer, S.;
FASEB Journal
2006 , 20:434-443

Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry
Merrill, Jr., A.H.; Sullards, M.C.; Allegood, J.C.; Kelly, S.; Wang, E.;
Methods. 2005 ; 36(2):207-24
Journal Abstract

Metabolite Identification/Metabolomics

(Click here to return to application menu)

Advances in structure elucidation of small molecules using mass spectrometry
Kind, T.; Fiehn, O.
Bioanal. Rev. 2010; 2(1):23-60

(13)C Isotope-Labeled Metabolomes Allowing for Improved Compound Annotation and Relative Quantification in Liquid Chromatography-Mass Spectrometry-based Metabolomic Research
Giavalisco, P.; Kohl, K.; Hummel, J.; Seiwert, B.; Willmitzer, L.
Anal Chem. 2009 Jul 9. [Epub ahead of print]

Discovering natural products from myxobacteria with emphasis on rare producer strains in combination with improved analytical methods
Garcia, R.O.; Krug, D.; Müller, R. Methods Enzymol. 2009;458:59-91
Journal Abstract

Negative ion ‘chip-based’ nanospray tandem mass spectrometry for the analysis of flavonoids in glandular trichomes of Lychnophora ericoides Mart. (Asteraceae)
Gobbo-Neto. L.; Gates, P.J.; Lopes, N.P.
Rapid Commun Mass Spectrom. 2008 Dec;22(23):3802-8
Journal Abstract

High-resolution direct infusion-based mass spectrometry in combination with whole 13C metabolome isotope labeling allows unambiguous assignment of chemical sum formulas
Giavalisco, P.; Hummel, J.; Lisec, J.; Inostroza, A.C.; Catchpole, G.; Willmitzer, L. Anal Chem. 2008 Dec 15;80(24):9417-25
Journal Abstract

Rapid metabolite identification with sub parts-per-million mass accuracy from biological matrices by direct infusion nanoelectrospray ionization after clean-up on a ZipTip and LTQ/Orbitrap mass spectrometry
Erve, J.C.; Demaio, W.; Talaat, R.E.
Rapid Commun Mass Spectrom. 2008 Oct;22(19):3015-26
Journal Abstract

Dual negative precursor ion scan approach for rapid detection of glutathione conjugates using liquid chromatography/tandem mass spectrometry
Mahajan, M.K.; Evans, C.A.
Rapid Commun Mass Spectrom. 2008 Apr;22(7):1032-40

Comparison of a two-dimensional liquid chromatography/mass spectrometry approach with a chip-based nanoelectrospray device for structural elucidation of metabolites in a human ADME study using a quadrupole time-of-flight mass spectrometer
Trunzer, M.; Graf, D.; Kiffe, M.
Rapid Commun. Mass Spectrom. 2007; 21(6):937-44
Journal Abstract

Dynamic Range and Mass Accuracy of Wide-Scan Direct Infusion Nanoelectrospray Fourier Transform Ion Cyclotron Resonance Mass Spectrometry-Based Metabolomics Increased by the Spectral Stitching Method
Southam, A.D.; Payne, T.G.; Cooper, H.J.; Arvanitis, T.N.; Viant, M.R.
Anal. Chem. 2007; 79:4595-4602
Journal Abstract

Controlled Protein Precipitation in Combination with Chip-Based Nanospray Infusion Mass Spectrometry. An Approach for Metabolomics Profiling of Plasma
Boernsen, K.O.; Gatzek, S.; Imbert, G.;
Anal. Chem. 2005; 77(22):7255-64
Journal Abstract

Identification of a novel glutathione adduct of diclofenac, 4′-hydroxy-2′-glutathion-deschloro-diclofenac, upon incubation with human liver microsomes
Yu, L. J.; Chen, Y.; Deninno, M. P.; O’Connell, T. N.; Hop, C. E.
Drug Metab Dispos. 2005 Apr.;33(4):484-8. [Epub 2005 Jan 7]

The combination of liquid chromatography/tandem mass spectrometry and chip-based infusion for improved screening and characterization of drug metabolites
Staack, R.F.; Varesio, E.; Hopfgartner, G.
Rapid Commun. Mass Spectrom. 2005; 19:618–626
Journal Abstract

Metabolite fingerprinting: detecting biological features by independent component analysis
Scholz, M.; Gatzek, S.; Sterling, A.; Fiehn, O.; Selbig, J.;
Bioinformatics. 2004, 20(15):2447-54 [Epub 2004 Apr 15]

Quantitation of midazolam in human plasma by automated chip-based infusion nanoelectrospray tandem mass spectrometry
Kapron, J.T.; Pace, E.; Van Pelt, C.K.; Henion, J.
Rapid Commun Mass Spectrom. 2003;17(18):2019-26
Journal Abstract

Noncovalent Interactions

(Click here to return to application menu)

Quantifying Protein-Ligand Binding Constants using Electrospray Ionization Mass Spectrometry: A Systematic Binding Affinity Study of a Series of Hydrophobically Modified Trypsin Inhibitors
Cubrilovic, D.; Biela, A.; Sielaff, F.; Steinmetzer, T.; Klebe, G.; Zenobi, R.
J Am Soc Mass Spectrom. 2012 Oct;23(10):1768-77. Epub 2012 Aug 7

Molecular recognition at protein surface in solution and gas phase: Five VEGF peptidic ligands show inverse affinity when studied by NMR and CID-MS
Dyachenko, A.; Goldflam, M.; Vilaseca, M.; Giralt, E.
Biopolymers. 2010;94(6):689-700.
Journal Abstract

An integrative approach combining noncovalent mass spectrometry, enzyme kinetics and X-ray crystallography to decipher Tgt protein-protein and protein-RNA interaction
Ritschel, T.; Atmanene, C.; Reuter, K.; Van Dorsselaer, A.; Sanglier-Cianferani, S.; Klebe, G.
J Mol Biol. 2009 Nov 6;393(4):833-47. [Epub 2009 Jul 21]
Journal Abstract

Gas Phase Stabilization of Noncovalent Protein Complexes Formed by Electrospray Ionization
Bagal, D.; Kitova, E. N.; Liu, L.; El-Hawiet, A.; Schnier, P. D.; Klassen, J. S.
Anal Chem. 2009 Sep 15;81(18):7801-6.
Journal Abstract

HDX-ESI-MS Reveals Enhanced Conformational Dynamics of the Amyloidogenic Protein ß2-Microglobulin upon Release from the MHC-1
Hodkinson, J.P.; Jahn, T.R.; Radford, S.E.; Ashcroft, A.E.
J Am Soc Mass Spectrom. 2009 Feb.;20(2):278-86. [Epub 2008 Oct 17]

Deciphering drift time measurements from travelling wave ion mobility spectrometry-mass spectrometry studies
Smith, D.P.; Knapman, T.W.; Campuzano, I.; Malham, R.W.; Berryman, J.T.; Radford, S.E.; Ashcroft, A.E.
Eur J Mass Spectrom (Chichester, Eng). 2009;15(2):113-30

Identification of Endocrine-Disrupting Compounds Using Nanoelectrospray Ionization Mass Spectrometry
Bovet, C.; Ruff, M; Wortmann, A.; Eiler, S.; Granger, F.; Gerrits, B.; Moras, D.; Zenobi, R.
CHIMIA International Journal for Chemistry. 2008, May. 62(5): 329-334(6)
Journal Abstract

Real-Time Monitoring of Protein Complexes Reveals their Quaternary Organization and Dynamics
Painter, A.J.; Jaya, N.; Basha, E.; Vierling, E.; Robinson, C.V.; Benesch, J.L.P.
Chem. Biol. 2008, Mar.;15(3):246-53

Which Electrospray-Based Ionization Method Best Reflects Protein-Ligand Interactions Found in Solution? A Comparison of ESI, nanoESI, and ESSI for the Determination of Dissociation Constants with Mass Spectrometry
Jecklin, M.C.; Touboul, D.; Bovet, C.; Wortmann, A.; Zenobi, R.
J. Am. Soc. Mass Spectrom. 2008, Mar.;19(3):332-43 [ Epub 2007 Nov 19]
Journal Abstract

Determination of active enzyme concentration using activity-based probes and direct mass spectrometric readout
Bovet, C.; Zenobi, R.;
Anal. Biochem.. 2008, Feb. 15 ; 373(2):380-2 [Epub 2007 Nov 6]
Journal Abstract

Binding constant determination of high-affinity protein–ligand complexes by electrospray ionization mass spectrometry and ligand competition
Wortmann, A.; Jecklin, M.C.; Touboul, D.; Badertscher, M.; Zenobi, R.
J. Mass Spectrom. 2007, Dec. 11;43(5):600-608 [Epub ahead of print]
Journal Abstract

Estrogen receptor–ligand complexes measured by chip-based nanoelectrospray mass spectrometry: An approach for the screening of endocrine disruptors
Bovet, C.; Wortmann, A.; Eiler, S.; Granger, F.; Ruff, M.; Gerrits, B.; Moras, D.; Zenobi, R.
Prot. Sci. 2007 , 16:938-946

Direct Observation of Oligomeric Species formed in the Early Stages of Amyloid Fibril Formation using Electrospray Ionisation Mass Spectrometry
Smith, A.M.; Jahn, T.R.; Ashcroft, A.E.; Radford, S.E.;
J. Mol. Biol. 2006;364(1):9-19
Journal Abstract

Monitoring the Zinc Affinity of the Metallo-ß-Lactamase CphA by Automated nanoESI-MS
De Vriendt, K.; Van Driessche, G.; Devreese, B.; Bebrone, C.; Anne, C.; Frere, J.M.; Galleni, M.; Van Beeumen, J.;
J. Am. Soc. Mass. Spectrom. 2006 , 17(2):180-188
Journal Abstract

Studies on Ternary Metallo-ß Lactamase-Inhibitor Complexes Using Electrospray Ionization Mass Spectrometry
Selevsek,N.; Tholey, A.; Heinzle, E.; Lienard, B.; Oldham, N.J.; Schofield, C.J.; Heinz, U.; Adolph, H.W.; Frere, J.M.;
J. Am. Soc. Mass. Spectrom. 2006, 17:1000-1004
Journal Abstract

Real-time monitoring of enzymatice DNA hydrolysis by electrospray ionization mass spectrometry
van den Heuvel, R.H.H.; Gato, S.; Versluis, C.; Gerbaux, P.; Kleanthous, C.; Heck, A.J.R.
Nucleic Acids Res. 2005, 33(10):e96

Evaluation of automated nano-electrospray mass spectrometry in the determination of non-covalent protein-ligand complexes
De Vriendt, K.; Sandra, K., Desmet, T.; Nerinckx, W.; Van Beeumen, J.; Devreese, B.
Rapid Commun. Mass Spectrom. 2004, 18:3061-3067
Journal Abstract

Automated nano-electrospray mass spectrometry for protein-ligand screening by noncovalent interaction applied to human H-FABP and A-FABP
Benkestock, K.; Van Pelt, C.K.; ?kerud, T.; Sterling, A.; Edlund, P.-O.; Roeraade, J.
J. Biomol. Screen. 2003, 247-256
Journal Abstract

Use of a microchip device coupled with mass spectrometry for ligand screening of a multi-protein target
Keetch , C.A. ; Hernández, H.; Sterling , A.; Baumett, M.; Allen, M.H.; Robinson, C.V.
Anal. Chem. 2003, 75(18):4937-4941

Quantitative Determination of Noncovalent Binding Interactions Using Automated Nanoelectrospray Mass Spectrometry
Zhang, S.; Van Pelt, C.K.; Wilson, D.B.;
Anal. Chem. 2003, 75(13): 3010-3018

Post-Translational Modifications

(Click here to return to application menu)

Facile identification and quantitation of protein phosphorylation via beta-elimination and Michael addition with natural abundance and stable isotope labeled thiocholine
Chen, M.; Su, X.; Yang, J.; Jenkins, C.M.; Cedars, A.M.; Gross, R.W.
Anal Chem. 2010 Jan 1;82(1):163-71
Journal Abstract

GPIomics: global analysis of glycosylphosphatidylinositol-anchored molecules of Trypanosoma cruzi
Nakayasu, E.S.; Yashunsky, D.V.; Nohara, L.L.; Torrecilhas, A.C.; Nikolaev, A.V.; Almeida, I.C.
Mol Syst Biol. 2009; 5:261. [Epub 2009 Apr 7]

The effect of phosphorylation on the electron capture dissociation of peptide ions
Creese, A.J.; Cooper, H.J.
J Am Soc Mass Spectrom. 2008 Sep;19(9):1263-74. [Epub 2008 May 28]

Mapping of lysine monomethylation of linker histones in human breast and its cancer
Lu, A.; Zougman, A.; Pudelko, M.; Bebenek, M.; Ziólkowski, P.; Mann, M.; Wisniewski, J.R.
J Proteome Res. 2009 Sep;8(9):4207-15.
Journal Abstract

The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src
Akbarzedeh, S.; Wheldon, L.M.; Sweet, S.M.; Talma, S.; Mardakheh, F.K.; Heath, J.K.
PLoS One. 2008 Mar 26;3(3):e1873.

Fine mapping of posttranslational modifications of the linker histone H1 from Drosophila melanogaster
Villar-Garea, A.; Imhof, A.
PLoS One. 2008 Feb 6;3(2):e1553

Nanoelectrospray peptide mapping revisited: Composite survey spectra allow high dynamic range protein characterization without LCMS on an orbitrap mass spectrometer
Lu, A.; Waanders, L.F.; Almeida, R.; Li, G.; Allen, M.; Cox, J.; Olsen, J.V.; Bonaldi, T.; Mann, M.
Int. J. of Mass Spectrom. 2007, 268:158-167
Journal Abstract

Cellular expression and crystal structure of the murine cytomegalovirus major histocompatibility complex class I-like glycoprotein, m153
Mans, J.; Natarajan, K.; Balbo, A.; Schuck, P.; Eikel, D.; Hess, S.; Robinson, H.; Šimic, H.; Jonjic, S.; Tiemessen, C.T.; Margulies, D.H.
J. Biol. Chem. 2007, Nov. 30; 282(48):35247-58. [Epub ahead of print 2007 Sept 26]

Galactosaminoglycan function and oligosaccharide structure determination
Seidler, D.G.; Peter Katalinic, J.; Zamfir, A.D.
Scient. World J. 2007;19:233-241
Journal Abstract

Human gliosarcoma-associated ganglioside composition is complex and highly distinctive as evidenced by high-performance mass spectrometric determination and structural characterization
Vukelic, Z.; Kalanj Bognar, S.; Froesch, M.; Bindila, L.; Radic, B.; Allen, M.; Peter Katalinic, J.; Zamfir, A.D.
Glycobiology. 2007;17, 504 – 515 [Epub 2007 Feb 9]

Identification of Single and Double Sites of Phosphorylation by ECD FT-ICR/MS in Peptides Related to the Phosphorylation Site Domain of the Myristoylated
Alanine-Rich C Kinase Protein; Woodling, K.A.; Eyler, J.R.; Tsybin, Y.O.; Nilsson, C.L.; Marshall, A.G.; Edison, A.S.; Al-Naggar, I.M.; Bubb, M.R.
J. Am. Soc. Mass. Spectrom. 2007;18:2137–2145
Journal Abstract

Ultralow-volume fraction collection from NanoLC columns for mass spectrometric analysis of protein phosphorylation and glycosylation
Corso, T.N.; Van Pelt, C.K.; Li, J.; Ptak, C.; Huang X.
Anal Chem. 2006 Apr 1;78(7):2209-19
Journal Abstract

Analysis of human hippocampus gangliosides by fully-automated chip-based nanoelectrospray tandem mass spectrometry
Vukelica, Z.; Zareib, M.; Peter-Katalinic, J.; Zamfir, A.D.
J. Chromatogr. A. 2006;1130:238-245
Journal Abstract

Determination of Mammillaria gracillis N-glycan patters by ESI Q-TOF mass spectrometry
Balen, B.; Zamfir, A.D.; Vakhrushev, S.; Krsnik-Rasol, M.; Peter Katalinic, J.
Croat. Chem. Acta. 2006;78:463-477
Journal Abstract

Characterization of Protein Glycosylation Using Chip-Based Infusion Nanoelectrospray Linear Ion Trap Tandem Mass Spectrometry
Zhang, S.; Chelius, D.
J. Biomol. Tech. 2004;15:120-133

Coupling of fully automated chip electrospray to fourier transform ion cyclotron resonance mass spectrometry for high-performance glycoscreening and sequencing
Froesch, M.; Bindila, L.M.; Baykut, G.; Allen, M.; Peter-Katalinic, J.; Zamfir, A.D.
Rapid Commun. Mass Spectrom. 2004;18(24):3084 – 3092
Journal Abstract

Fully Automated Chip-Based Mass Spectrometry for Complex Carbohydrate System Analysis;
Zamfir, A.;Vakhrushev, S.; Sterling , S.; Niebel, H.J.; Allen, M.; Peter-Katalinic, J.
Anal. Chem. 2004;76:2046-2054
Journal Abstract

Fully-automated chip-based nanoelectrospray tandem mass spectrometry of gangliosides from human cerebellum;
Zamfir, A.; Vukelic, Z.; Bindila, L.; Peter-Katalinic, J.; Almeida, R.; Sterling, A.; Allen, M.;
J. Am. Soc. Mass. Spectrom. 2004;15(11):1649-57
Journal Abstract

Off-line capillary electrophoresis/fully automated nanoelectrospray chip quadrupole time-of-flight mass spectrometry and tandem mass spectrometry for glycoconjugate analysis
Bindila, L.; Almeida, R.; Sterling, A.; Allen, M.; Peter-Katalinic, J.; Zamfir, A.
J. Mass Spectrom. 2004;39:1190–1201
Journal Abstract

Protein Identification

(Click here to return to application menu)

Combined bottom-up and top-down mass spectrometry analyses of the pattern of post-translational modifications of Drosophila melanogaster linker histone H1
Carles Bonet-Costa, Marta Vilaseca, Claudio Diema, Olivera Vujatovic, Alejandro Vaquero, Núria Omeñaca, Lucía Castejón, Jordi Bernués, Ernest Giralt, Fernando Azorín
Journal of Proteomics, Available online 27 May 2012, ISSN 1874-3919, 10.1016/j.jprot.2012.05.034.

Structure of Triplex DNA in the Gas Phase
Annalisa Arcella, Guillem Portella, Maria Luz Ruiz, Ramon Eritja, Marta Vilaseca, Valérie Gabelica, and Modesto Orozco
Journal of the American Chemical Society 2012 134 (15), 6596-6606

Multi-Segment Direct Inject nano-ESI-LTQ-FT-ICR-MS/MS For Protein Identification
Chen, J.; Canales, L.; Neal, R.E.
Proteome Sci. 2011 Jul 7;9:38

Identification of the growth-hormone-releasing peptide-2 (GHRP-2) in a nutritional supplement
Thomas, A.; Kohler, M.; Mester, J.; Geyer, H.; Schänzer, W.; Petrou, M.; Thevis, M.
Drug Test Anal. 2010 Mar;2(3):144-8.
Journal Abstract

Nanoelectrospray with ion-trap mass spectrometry for the determination of beta-casomorphins in derived milk products
Juan-García, A.; Font, G.; Juan, C.; Picó, Y.
Talanta. 2009 Nov 15;80(1):294-306. [Epub 2009 Jul 4]
Journal Abstract

Two highly conserved cysteine residues in HPV16 L2 form an intramolecular disulfide bond and are critical for infectivity in human keratinocytes
Campos, S.K.; Ozbun, M.A.
PLoS One. 2009; 4(2):e4463. [Epub 2009 Feb 13]
Journal Abstract

Towards Heat-stable Oxytocin Formulations: Analysis of Degradation Kinetics and Identification of Degradation Products
Hawe, A.; Poole, R.; Romeijn, S.; Kasper, P.; van der Heijden, R.; Jiskoot, W.
Pharm Res. 2009 Jul;26(7):1679-88. [Epub 2009 Apr 3]

Detection and structural features of the betaB2-B3-crystallin heterodimer by radical probe mass spectrometry (RP-MS)
Diemer, H.; Atmanene, C.; Sanglier, S.; Morrissey, B.; Van Dorsselaer, A.; Downard, K.M.
J Mass Spectrom. 2009 May;44(5):803-12
Journal Abstract

DNA sampling: a method for probing protein binding at specific loci on bacterial chromosomes
Butala, M.; Busby, S.J.; Lee, D.J.
Nucleic Acids Res. 2009 Apr;37(5):e37. [Epub 2009 Jan 30]

Proteomics of the TRAP-induced platelet releasate
Piersma, S.R.; Broxterman, H.J.; Kapci, M.; de Haas, R.R.; Hoekman, K.; Verheul, H.M.; Jiménez, C.R.
J Proteomics. 2009 Feb 15;72(1):91-109. [Epub 2008 Nov 8]
Journal Abstract

Computational analysis and experimental validation of gene predictions in Toxoplasma gondii
Dybas, J. M., Madrid-Aliste, C. J., Che, F. Y., Nieves, E., Rykunov, D., Hogue, R., Weiss, L. M., Kim, K., Fiser, A.
PLoS One. 2008 ;3(12):e3899. [Epub 2008 Dec 9]

Technical Brief: a novel strategy for enrichment of trabecular meshwork protease proteome
Picciani, R.; Junk, A. K.; Bhattacharya, S. K.
Mol Vis. 2008 May 14;14:871-7

An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti
Ribeiro, J. M. C.; Arcà, B.; Lombardo, F.; Calvo, E.; Phan, V. M.; Chandra, P. K.; Wikel, S. K.
BMC Genomics. 2007 Jan 4;8:6

A Systematic Evaluation of Chip-Based Nanoelectrospray Parameters for Rapid Identification of Proteins from a Complex Mixture
Pereira-Medrano, A.G.; Sterling , A.; Snijders, A.P.L.; Reardon, K.F.; Wright, P.C.
J. Am. Soc. Mass. Spectrom. 2007 , 18(9):1714-25 [Epub 2007 Jun 30]
Journal Abstract

Global analysis of community-associated methicillin-resistant Staphylococcus aureus exoproteins reveals molecules produced in vitro and during infection
Burlak, C.; Hammer, C.H.; Robinson, M.-A.; Whitney, A.R. McGavin, M.J.; Kreiswirth, B.N. DeLeo, F.R.
Cell Micriobiol. 2007; 9(5):1172-90 [Epub 2007 Jan 9]

Investigation of the presence of b ions in electron capture dissociation mass spectra
Cooper, H.J.;
J. Am. Soc. Mass. Spectrom. 2005;16:1932–1940
Journal Abstract

Protein identification using sequential ion/ion reactions and tandem mass spectrometry
Coon, J.J.; Ueberheide, B.; Syka, J.E.P.; Dryhurst, D.D.; Ausio, J.; Shabanowitz, J.; Hunt, D.F.
PNAS 2005;102(27):9463-9468
Journal Abstract

Disposable Chromatography for a High-Throughput Nano-ESI/MS and Nano-ESI/MS-MS Platform
Williams, J.G.; Tomer, K.B.
J Am Soc Mass Spectrom. 2004 Sep;15(9):1333-40

Hybrid Ion Trap-Fourier Transform-Ion Cyclotron Resonance for High-Performance Analysis
Taylor, L.
Am. Lab. 2004 Jan:30-35

Chip-based nanoelectrospray mass spectrometry for protein characterization
Zhang, S.; Van Pelt, C.K.
Expert Rev. Proteomics. 2004:1(4):449-468
Journal Abstract

Automated chip-based nanoelectrospray-mass spectrometry for rapid identification of proteins separated by two-dimensional gel electrophoresis
Zhang, S.; Van Pelt, C.K.; Henion, J.D.
Electrophoresis 2003;24:3620-3623
Journal Abstract

Surface-alkylated polystyrene monolithic columns for peptide analysis in capillary liquid chromatography-electrospray ionization mass spectrometry
Huang, X.; Zhang, S.; Schultz, G.A.; Henion, J.
Anal Chem.
2002 May 15;74(10):2336-44
Journal Abstract

Characterization of a Fully Automated Nanoelectrospray System with Mass Spectrometric Detection for Proteomic Analyses
Van Pelt, C.K.; Zhang, S.; Henion, J.D.
J. Biomol. Tech., 2002;13:72-84

Top-Down Proteomics

(Click here to return to application menu)

Pressurized pepsin digestion in proteomics: An automatable alternative to trypsin for integrated top-down bottom-up proteomics
López-Ferrer, D.; Petritis, K.; Robinson, E. W.; Hixson, K. K.; Tian, Z.; Lee, J. H.; Lee, S. W.; Tolic, N.; Weitz, K. K.; Belov, M. E.; Smith, R. D.; Pasa-Tolic, L.
Mol Cell Proteomics. 2011 Feb;10(2):M110.001479. [Epub 2010 Jul 12]
Journal Article

Top-Down Proteomics Reveals Novel Protein Forms Expressed in Methanosarcina acetivorans
Ferguson, J.T.; Wenger, C.D.; Metcalf, W.W.; Kelleher, N.L.
J Am Soc Mass Spectrom. 2009 Sep;20(9):1743-50. [Epub 2009 Jun 6]
Journal Abstract

Top-down high-resolution mass spectrometry of cardiac myosin binding protein C revealed that truncation alters protein phosphorylation state
Ge, Y.; Rybakova, I.N.; Xu, Q.; Moss, R.L.
Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12658-63. [Epub 2009 Jun 16]

Delineating Anopheles gambiae coactivator associated arginine methyltransferase 1 automethylation using top-down high resolution tandem mass spectrometry
Kuhn, P.; Xu, Q.; Cline, E.; Zhang, D.; Ge, Y.; Xu, W.
Protein Sci. 2009 Jun;18(6):1272-80
Journal Abstract

Activated Ion Electron Capture Dissociation (AI ECD) of proteins: synchronization of infrared and electron irradiation with ion magnetron motion
Mikhailov, V.A.; Cooper, H.J.
J Am Soc Mass Spectrom. 2009 May; 20(5):763-71. [Epub 2008 Dec 31]

An integrated top-down and bottom-up strategy for broadly characterizing protein isoforms and modifications
Wu, S.; Lourette, N.M.; Tolic, N.; Zhao, R.; Robinson, E.W.; Tolmachev, A.V.; Smith, R.D.; Pasa-Tolic, L.
J Proteome Res. 2009 Mar;8(3):1347-57
Journal Abstract

Top-Down Approaches for Measuring Expression Ratios of Intact Yeast Proteins Using Fourier Transform Mass Spectrometry
Du, Y.; Parks, B.A.; Sohn, S.; Kwast, K.E.; Kelleher, N.L.
Int. J. of Mass Spectrom. 2006 , 234:686-694
Journal Abstract

Top-down protein sequencing and MS 3 on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer
Macek, B.; Waanders, L.; Olsen, J.V.; Mann, M.
Mol. Cell. Prot. 2006;5:949-958

Construction of a hybrid quadrupole/Fourier transform ion cyclotron resonance mass spectrometer for versatile MS/MS above 10 kDa
Patrie, S.M.; Charlebois, J.P.; Whipple, D.; Kelleher, N.L.; Hendrickson, C.L.; Quinn, J.P.; Marshall, A.G.; Mukhopadhyay, B.
J. Am. Soc. Mass. Spectrom. 2004;15(7):1099-108
Journal Abstract

Improved Molecular Weight-Based Processing of Intact Proteins for Interrogation by Quadrupole-Enhanced FT MS/MS
Du, Y.; Meng, F.; Patrie, S.M.; Miller, L.M.; Kelleher, N.L.
J. Proteome Res. 2004;3(4):801–806
Journal Abstract

Molecular-Level Description of Proteins from Saccharomyces cerevisiae Using Quadrupole FT Hybrid Mass Spectrometry for Top Down Proteomics
Meng, F.; Du, Y.; Miller, L.M.; Patrie, S.M.; Robinson, D.E.; Kelleher, N.L.
Anal. Chem. 2004; 76(10):2852 -2858
Journal Abstract

Strategies for automating top down proteomics with Q-FT ICR MS
Patrie, S.M.; Robinson, D.E.; Meng, F.; Kelleher, N.L
Int. J. Mass Spectrom. 2004;234:175-184
Journal Abstract

Targeted Analysis and Discovery of Post-Translational Modifications in Proteins from Methanogenic Archaea by Top Down Mass Spectrometry
Forbes, A.J.; Patrie, S.M.; Taylor, G.K.; Kim, Y.B.; Kelleher, N.L.
PANS 2004, 101(9):2678-2683


(Click here to return to application menu)

Analysis of oversulfation in biglycan chondroitin/dermatan sulfate oligosaccharides by chip-based nanoelectrospray ionization multistage mass spectrometry
Flangea, C.; Sisu, E.; Seidler, D. G., Zamfir, A. D.
Anal Biochem. [Epub 2011 Sep 22 ahead of print]
Journal Abstract

Combining size-exclusion chromatography and fully automated chip-based tandem mass spectrometry for structural analysis of chondroitin/dermatan sulfate in human decorin
Zamfir, A. D.; Flangea, C.; Sisu, E.; Seidler, D. G.; Peter-Katalinić, J.
Electrophoresis. 2011 Jun;32(13):1639-46. [Epub 2011 Jun 6]
Journal Abstract

Photochemical degradation of citrate buffers leads to covalent acetonation of recombinant protein therapeutics
Valliere-Douglass, J. F.; Connell-Crowley, L.; Jensen, R.; Schnier, P. D.; Trilisky, E.; Leith, M.; Follstad, B. D.; Kerr, J.; Lewis, N.; Vunnum, S.; Treuheit, M. J.; Balland, A.; Wallace, A.
Protein Sci. 2010 Nov;19(11):2152-63.

The N-glycome of human plasma
Stumpo, K.A.; Reinhold, V.N.
J Proteome Res. 2010 Sep 3;9(9):4823-30.

Journal Abstract

A multi-method approach toward de novo glycan characteriztion: A Man-5 case-study
Prien, J.M.; Prater, B.D.; Cockrill, S.L.
Glycobiology. 2010 May;20(5):629-47. [Epub 2010 Jan 27]
Journal Abstract

Glutamine-linked and non-consensus asparagine-linked oligosaccharides present in human recombinant antibodies define novel protein glycosylation motifs
Valliere-Douglass, J.F.; Eakin, C.M.; Wallace, A..; Ketchem, R.R.; Wang, W.; Treuheit, M.J.; Balland, A.
J Biol Chem. 2010 May 21;285(21):16012-22. [Epub 2010 Mar 16]
Journal Abstract

Mass spectrometric-based stable isotopic 2-aminobenzoic acid glycan mapping for rapid screening of biotherapeutics
Prien, J.M.; Prater, B.D.; Qin, Q.; Cockrill, S.L.
Anal Chem. 2010 Feb 15;82(4):1498-508
Journal Abstract

Determination of sulfation pattern in brain glycosaminoglycans by chip-based electrospray ionization ion trap mass spectrometry
Flangea, C.; Schiopu, C.; Sisu, E.; Serb, A.; Przybylski, M.; Seidler, D.G.; Zamfir, A.D.
Anal Bioanal Chem. 2009 Dec;395(8):2489-98. [Epub 2009 Oct 14]
Journal Abstract

Discrimination of GalNAc (4S/6S) sulfation sites in chondroitin sulfate disaccharides by chip-based nanoelectrospray multistage mass spectrometry
Flangea, C.; Serb, A. F.; Schiopu, C.; Tudor, S.; Sisu, E.; Seidler, D. G.; Zamfir, A. D.
Cent. Eur. J. Chem. 2009; 7(4):752–759.

Asparagine-linked oligosaccharides present on a non-consensus amino acid sequence in the CH1 domain of human antibodies
Valliere-Douglass, J.F.; Kodama, P.; Mujacic, M.; Brady, L.J.; Wang, W.; Wallace, A.; Yan, B.; Reddy, P.; Treuheit, M.J.; Balland, A.
J Biol Chem. 2009 Nov 20;284(47):32493-506. [Epub 2009 Sep 18]
Journal Abstract

Extending Mass Spectrometry Contribution to Therapeutic Monoclonal Antibody Lead Optimization: Characterization of Immune Complexes Using Noncovalent ESI-MS
Atmanene, C.; Wagner-Rousset, E.; Malissard, M.; Chol, B.; Robert, A.; Corvaïa, N.; Dorsselaer, A.V.; Beck, A.
Anal Chem. 2009 Aug 1;81(15):6364-73
Journal Abstract

Coupling of fully automated chip-based electrospray ionization to high-capacity ion trap mass spectrometer for ganglioside analysis
Almeida, R.; Mosoarca, C.; Chirita, M.; Udrescu ,V.; Dinca, N.; Vukelic, Z.; Allen, M.; Zamfir, A.D.
Anal Biochem. 2008 Jul 1;378(1):43-52. [Epub 2008 Mar 28]
Journal Abstract

Other Applications

(Click here to return to application menu)

A protein epitope signature Tag (PrEST) library allows SILAC-based absolute quantification and multiplexed determination of protein copy numbers in cell lines
Zeiler, M.; Straube, W. L.; Uhlen, M.; Mann, M.
Mol Cell Proteomics.[Epub 2011 Sep 30]

High prestige Royal Purple dyed textiles from the Bronze Age royal tomb at Qatna, Syria Gates, P.
Antiquity. 2009;83(322):1109-1118
Journal Abstract

A fragmentation study of di-Acidic mycosporine-like amino Acids in electrospray and nanospray mass spectrometry
CardozoI, K.H.M.; Vessecchi, R.; Galembeck, S.E.; Guaratini, T.; Gates, P.; Pinto, E.; Lopes, N.P.; Colepicolo, P.
J. Braz. Chem. Soc. 2009;20(9): 625-1631

The reality of lab-on-a-chip technology for the mass spectrometry laboratory
Henion, J. LCGC North America, 2009 Oct 1

Semi-automated tandem mass spectrometric (MS/MS) triple quadrupole operating parameter optimization for high-throughput MS/MS detection workflows
Geddes, K., Adamson, G., Dube, N., Crathern, S., King, R.C.
Rapid Commun Mass Spectrom. 2009 May;23(9):1303-12
Journal Abstract

Electron Capture Dissociation and Collision-Induced Dissociation of Metal Ion (Ag+, Cu2+, Zn2+, Fe2+, and Fe3+) Complexes of Polyamidoamine (PAMAM) Dendrimers
Kaczorowska, M.A.; Cooper, H.J.
J Am Soc Mass Spectrom.
2009 Apr;20(4):674-81. [Epub 2008 Dec 27]

Automated electrospray ionization FT-ICR mass spectrometry for petroleum analysis
Kim, S.; Rodgers, R.P.; Blakney, G.T.; Hendrickson, C.L.; Marshall, A.G.
J Am Soc Mass Spectrom. 2009 Feb;20(2):263-8. [Epub 2008 Oct 9]

Single amino acid sequence polymorphisms in rat cardiac troponin revealed by top-down tandem mass spectrometry
Sancho Solis, R.; Ge, Y.; Walker, J.W.
J Muscle Res Cell Motil. 2008;29(6-8):203-12. [Epub 2009 Jan 23]

Deciphering drift time measurements from travelling wave ion mobility spectrometry-mass spectrometry studies
Smith, D.P.; Knapman, T.W.; Campuzano, I.; Malham, R.W.; Berryman, J.T.; Radford, S.E.; Ashcroft, A.E.
Eur J Mass Spectrom (Chichester, Eng). 2009;15(2):113-30

Electron Capture Dissociation, Electron Detachment Dissociation, and Collision-Induced Dissociation of Polyamidoamine (PAMAM) Dendrimer Ions with Amino, Amidoethanol, and Sodium Carboxylate Surface Groups
Kaczorowska, M.A.; Cooper, H.J.
J Am Soc Mass Spectrom. 2008 Sep;19(9):1312-9. [Epub 2008 Jun 28]

Measurement of total acid number (TAN) and TAN boiling point distribution in petroleum products by electrospray ionization mass spectrometry
Qian, K.; Edwards, K.E.; Dechert, G.J.; Jaffe, S.B.; Green, L.A. ; Olmstead, W.N.
Anal Chem. 2008, Feb. 1; 80(3):849-55 [Epub 2008 Jan 8]
Journal Abstract

Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry
Kind, T.; Fiehn, O.
BMC Bioinformatics.2007;Mar 27;8:105

At-line coupling of UPLC to chip-electrospray-FTICR-MS
Li, X.; Fekete, A.; Englmann, M.; Frommberger, M.; Lv, S.; Chen, G.; Schmitt-Kopplin, P.
Anal. Bioanal. Chem. 2007;389(5):1439-46 [Epub ahead of print]
Journal Abstract

Differential ionisation of natural antioxidant polyenes in electrospray and nanospray mass spectrometry
Guaratini, T.; Gates, P.J.; Pinto, E.; Colepicolo, P.; Lopes, N.P.
Rapid Commun. Mass Spectrom. 2007;21: 3842–3848
Journal Abstract

Fragmentation studies of monensin A and B in negative electrospray and nanospray tandem mass spectrometry
Sousa-Junior, J.N.; Gates, P.J.; Lopes, N.P.
Eur. J. Mass Spectrom. 2007;13:191-198

Resolving Oligomers from Fully Grown Polymers with IMS-MS
Trimpin, S.; Plasencia, M.; Isailovic, D.; Clemmer, D.E.;
Anal. Chem. 2007;79:7965-7974
Journal Abstract

Quantitation of cotinine in nonsmoker saliva using chip-based nanoelectrospray tandem mass spectrometry
Tomkins, B.A.; Van Berkel, G.J.; Jenkins, R.A.; Counts, R.W.
J Anal Toxicol. 2006 Apr;30(3):178-86

Mechanism for the elimination of aromatic molecules from polyenes in tandem mass spectrometry
Guaratini, T.; Lopes, N.P.; Pinto, E.; Colepicolo, P.; Gates, P.J.
Chem. Commun. (Camb). 2006 Oct. 21;389(5):1439-46 [Epub ahead of print]
Journal Abstract

Letter: Radical ion and protonated molecule formation with retinal in electrospray and nanospray
Guaratini, T.; Gates, P.J.; Cardozo, K.H.; Campos , P.M.; Colepicolo, P.; Lopes, N.P.
Eur. J. Mass Spectrom. ( Chichester , Eng. ). 2006;12(1):71-4

Automated nanospray using chip-based emitters for the quantitative analysis of pharmaceutical compounds
Corkery, L.J.; Henrianna, P.; Schneider, B.B.; Covey, T.R.; Siu, K.W.
J Am Soc Mass Spectrom.
2005 Mar;16(3):363-9. [Epub 2005 Jan 19]

A fully automated nanoelectrospray tandem mass spectrometric method for analysis of Caco-2 samples
Van Pelt, C.K.; Zhang, S.; Fung, E.; Chu, I.; Liu, T.; Li, C.; Korfmacher, W.A.; Henion, J.
Rapid Commun Mass Spectrom. 2003;17(14):1573-8
Journal Abstract

Detection of single nucleotide polymorphisms using electrospray ionization mass spectrometry: validation of a one-well assay and quantitative pooling studies
Zhang, S.; Van Pelt, C.K.; Huang, X.; Schultz, G.A.
J Mass Spectrom. 2002 Oct;37(10):1039-50
Journal Abstract

Electrospray ionization mass spectrometry-based genotyping: an approach for identification of single nucleotide polymorphisms
Zhang, S.; Van Pelt, C.K.; Schultz, G.A.
Anal Chem. 2001 May 1;73(9):2117-25
Journal Abstract

A fully integrated monolithic microchip electrospray device for mass spectrometry
Schultz, G.A.; Corso, T.N.; Prosser, S.J.; Zhang, S.
Anal Chem. 2000 Sep 1;72(17):4058-63
Journal Abstract