Gas Phase Sample Analysis by Volatile APCI (vAPCI)

Volatile Atmospheric Pressure Chemical Ionization (vAPCI) combined with Advion’s expression® compact mass spectrometer (CMS) is a fast and easy method to measure gases such as headspace and breath. The vAPCI provides a sample inlet linked by a heated transfer line to an APCI ion source, where the sample is ionized by corona discharge.

vAPCI enables chemists to:

  • Analyze Volatile Organic Compounds (VOCs) directly in the gas phase
  • Solvent-free APCI allows a greater range of compounds to be ionized compared to traditional APCI ion sources.
  • Publication quality data in < 30 seconds

Watch the video: Advion Volatile APCI Source

expression CMS Success Stories

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University of Cambridge, Ley Group

“I would recommend the system to any group that works with continuous flow chemistry, especially those that need real time analysis of stream compositions.”

Daniel E. Fitzpatrick, Ph. D Candidate, Student Researcher & Founder, ChemInventory

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Research Analyst – University of Leiden

“I incorporated the expression CMS as a TLC/MS system because of its simplicity, low cost and the brilliant combination with the Plate Express.”

Dr. Hans van den Elst, Research Analyst, University of Leiden

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Department of Chemistry – Creighton University

“It’s easy, walk-up use with straightforward swapping of ESI and APCI sources make it a reliable, productive tool for determining synthetic success.”

Dr. Martin Hulce, Department of Chemistry, Creighton University

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Cyclotron and Radiochemistry Research Program – UNC School of Medicine

“The convenience of having a mass spectrometer in our laboratory means that we can increase working efficiencies.”

Dr. Zibo Li, Department of Radiology UNC School of Medicine

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Recent expression CMS Publications

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expression CMS Application Notes

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iASAP Analysis of Air-Sensitive Compounds via Inert Sampling Techniques

Many chemical reactions carried out by synthetic chemists involve air-sensitive compounds such as metal catalysts and organometallics and must therefore be carried out in a glove box or using a Schlenk line to prevent oxidation and hydrolysis. Sampling and transportation of these samples to a mass spectrometer by an Atmospheric Solids Analysis Probe (ASAP ®)…

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Identification of a Pesticide Used in Lawn Care by vAPCI Compact Mass Spectrometry

At regular intervals throughout the year a local lawn service applies pesticides to the lawn surrounding the Advion headquarters in Ithaca, NY. The grass is very uniform and not a single dandelion or crabgrass plant is visible – so we wondered, what chemical do they use? After an application in the early spring, we sampled…

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Analyses of Different Grades of Olive Oil by Volatile Mass Spectrometry

In this application note, we demonstrate the use of the Advion expression CMS with a volatile APCI (vAPCI) ion source to analyze extra-virgin, virgin, and lampante olive oil samples. We show statistical analysis allowing us to categorize and identify olive oil samples by their grade. This technique allows us to test individual olive oil samples and…

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Classifying Cheeses by vAPCI Compact Mass Spectrometry

Cheese is one of the world’s most popular food types, with a wide variety available for consumers. The scents and flavors of cheeses, so characteristic to each type of cheese, stem from a complex mixture of chemicals, including free fatty acids. While this mixture is affected by a wide variety of factors we can use…

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