Gas Phase Sample Analysis by Volatile APCI (vAPCI)

Volatile Atmospheric Pressure Chemical Ionization (vAPCI) combined with Advion’s expression® compact mass spectrometer (CMS) is a fast and easy method to measure gases such as headspace and breath. The vAPCI provides a sample inlet linked by a heated transfer line to an APCI ion source, where the sample is ionized by corona discharge.

vAPCI enables chemists to:

  • Analyze Volatile Organic Compounds (VOCs) directly in the gas phase
  • Solvent-free APCI allows a greater range of compounds to be ionized compared to traditional APCI ion sources.
  • Publication quality data in < 30 seconds

Watch the video: Advion Volatile APCI Source

expression CMS Success Stories

See more success stories »

Mass Spectrometry Facility, Department of Chemistry University of Birmingham

“The Chemists are spending significantly more time running reactions.”

Chi Tsang, Experimental Officer

Read More »

Technical University Munich, Garching, Germany

“The expression CMS is the perfect MS system for any research laboratory involved in synthetic organic chemistry and chemical analytics or small molecules to proteins.”

Dr. Tobias A.M. Gulder, Professor

Read More »

New Path Molecular Ltd, United Kingdom

“expression CMS meets our requirements for an instrument that is intuitive to use, robust and capable of being maintained, expanded and serviced without manufacturer call outs.”

Dr. Gary Tarver, Lead Chemist

Read More »

Corden Pharma Switzerland LLC, Liestal, Switzerland

"We use the Advion expression CMS as a robust and versatile detector in our chromatographic processes, both MPLC and HPLC."

Dr. Markus Juza, Purification Expert

Read More »

Recent expression CMS Publications

See more publications »

expression CMS Application Notes

See more application notes »

Direct Analysis of Intact Proteins using the Advion Touch Express© Open Port Sampling Interface (OPSI) with the expressionL Compact Mass Spectrometer

Touch ExpressTM is a new sampling device for mass spec analysis using a technique developed by Gary Van Berkel and Vilmos Kertesz of Oak Ridge National Laboratory – the Open Port Sample Interface (OPSI). This fast, versatile sample inlet paired with the expression Compact Mass Spectrometer (CMS) provides simple molecular weight determination of surfaces, solids and liquids in < 30s.

Read More »

Fast Identification of Artificial Vanilla Flavor in Vanilla Extract by ASAP® Compact Mass Spectrometry

The expression CMS coupled with the Atmospheric Solids Analysis Probe (ASAP®) is used to quickly identify the presence of artificial vanilla, as well as confirm the purity of products marketed as such. This technique provides a fast and easy method for purity analysis.

Read More »

Fast Screening for Purity and Adulterants in Coconut Oil by ASAP® Compact Mass Spectrometry

The expression CMS coupled with the Atmospheric Solids Analysis Probe (ASAP®) is used to determine purity and detect adulterants in coconut oil. In this application note, pure coconut oil is tested against a sample of coconut oil adulterated with canola oil for comparative data analysis and a fast and easy method for purity analysis.

Read More »

iASAP Analysis of Air-Sensitive Compounds via Inert Sampling Techniques

Many chemical reactions carried out by synthetic chemists involve air-sensitive compounds such as metal catalysts and organometallics and must therefore be carried out in a glove box or using a Schlenk line to prevent oxidation and hydrolysis. Sampling and transportation of these samples to a mass spectrometer by an Atmospheric Solids Analysis Probe (ASAP ®)…

Read More »