'TIDES

A fast, affordable proteins and peptides analysis system

The ’tides express combines an extended mass range, compact mass spectrometer (expressionL CMS) with an easy-to-use HPLC gradient system with manual sample injector and optional UV detector for rapid, real-time analysis of large biomolecules at the point-of-need. Additional fragmentation analysis and charge deconvolution software tools provide the interpretation needed to easily confirm the identity of peptides, proteins and oligonucleotides.

  • Fast separation and mass analysis of proteins, peptides and oligonucleotides
  • Easy-to-use and affordable alternative to UHPLC/MSn
  • Positive analyte identification through fragmentation analysis and charge deconvolution software tools
  • Bench side analysis next to protein expression or SPPS synthesis systems

expression CMS Success Stories

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Research Analyst – University of Leiden

“I incorporated the expression CMS as a TLC/MS system because of its simplicity, low cost and the brilliant combination with the Plate Express.”

Dr. Hans van den Elst, Research Analyst, University of Leiden

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Department of Chemistry – Creighton University

“It’s easy, walk-up use with straightforward swapping of ESI and APCI sources make it a reliable, productive tool for determining synthetic success.”

Dr. Martin Hulce, Department of Chemistry, Creighton University

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Cyclotron and Radiochemistry Research Program – UNC School of Medicine

“The convenience of having a mass spectrometer in our laboratory means that we can increase working efficiencies.”

Dr. Zibo Li, Department of Radiology UNC School of Medicine

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Department for Homogeneous Catalysis, Max-Planck-Institut für Kohlenforschung

“Rapid characterization of reaction products combined with the lowest effort of sample preparation”

List Research Group, Max-Planck-Institut für Kohlenforschung

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Recent expression CMS Publications

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expression CMS Application Notes

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Identification of a Pesticide Used in Lawn Care by vAPCI Compact Mass Spectrometry

At regular intervals throughout the year a local lawn service applies pesticides to the lawn surrounding the Advion headquarters in Ithaca, NY. The grass is very uniform and not a single dandelion or crabgrass plant is visible – so we wondered, what chemical do they use? After an application in the early spring, we sampled…

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Analyses of Different Grades of Olive Oil by Vapor Mass Spectrometry

In this application note, we demonstrate the use of the Advion expression CMS with a vapor APCI (vAPCI) ion source to analyze extra-virgin, virgin, and lampante olive oil samples. We show statistical analysis allowing us to categorize and identify olive oil samples by their grade. This technique allows us to test individual olive oil samples…

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Classifying Cheeses by vAPCI Compact Mass Spectrometry

Cheese is one of the world’s most popular food types, with a wide variety available for consumers. The scents and flavors of cheeses, so characteristic to each type of cheese, stem from a complex mixture of chemicals, including free fatty acids. While this mixture is affected by a wide variety of factors we can use…

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Screening of Dietary Supplements by ASAP® Compact Mass Spectrometry

In this application note, we demonstrate the use of the Advion expressionL CMS with an atmospheric solids analysis probe (ASAP) ion source to analyze two supplements (figure 1) that contain DMBA, a synthetic stimulant that has not been tested on humans. The substance is the chemical cousin to drug DBAA, which is currently banned by…

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