expressionS CMS

for synthetic chemistry

The expression family of compact mass spectrometers provide essential information quickly and improves the chemist’s workflow. Designed with the synthetic organic chemist in mind, the expressionS is a flexible, transportable mass detector for small molecule analysis.

Unrivalled utility and flexibility

Reaction Monitoring

  • Compound identification for batch and flow chemistry
  • Confirm identity and purity quickly and accurately

Purification

  • Mass directed fraction collection for flash chromatography, Prep-LC and SFC

A versatile mass detector for:

  • Coupling to any (U)HPLC systems
  • Food safety
  • Water purity
  • Clinical diagnostics

VIDEO: How to Perform Easy & Rapid Compound ID

VIDEO: Mass Analysis from Liquids and Solids

VIDEO: Mass Analysis from TLC Plates

My recent initiative in providing and finding research funding has resulted in the purchase of the first Advion expression compact mass spectrometer to be installed in Australia in our research laboratory. This will improve the quality of the decision making process of my PG students in the research place leading to more efficient research outcomes and provide a mass spectral service to disciplines in our college at RMIT University.” Helmut Hugel – RMIT University, Australia

expression CMS Success Stories

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Mass Spectrometry Facility, Department of Chemistry University of Birmingham

“The Chemists are spending significantly more time running reactions.”

Chi Tsang, Experimental Officer

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Technical University Munich, Garching, Germany

“The expression CMS is the perfect MS system for any research laboratory involved in synthetic organic chemistry and chemical analytics or small molecules to proteins.”

Dr. Tobias A.M. Gulder, Professor

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New Path Molecular Ltd, United Kingdom

“expression CMS meets our requirements for an instrument that is intuitive to use, robust and capable of being maintained, expanded and serviced without manufacturer call outs.”

Dr. Gary Tarver, Lead Chemist

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Corden Pharma Switzerland LLC, Liestal, Switzerland

"We use the Advion expression CMS as a robust and versatile detector in our chromatographic processes, both MPLC and HPLC."

Dr. Markus Juza, Purification Expert

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Recent expression CMS Publications

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expression CMS Application Notes

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Direct Analysis of Intact Proteins using the Advion Touch Express© Open Port Sampling Interface (OPSI) with the expressionL Compact Mass Spectrometer

Touch ExpressTM is a new sampling device for mass spec analysis using a technique developed by Gary Van Berkel and Vilmos Kertesz of Oak Ridge National Laboratory – the Open Port Sample Interface (OPSI). This fast, versatile sample inlet paired with the expression Compact Mass Spectrometer (CMS) provides simple molecular weight determination of surfaces, solids and liquids in < 30s.

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Fast Identification of Artificial Vanilla Flavor in Vanilla Extract by ASAP® Compact Mass Spectrometry

The expression CMS coupled with the Atmospheric Solids Analysis Probe (ASAP®) is used to quickly identify the presence of artificial vanilla, as well as confirm the purity of products marketed as such. This technique provides a fast and easy method for purity analysis.

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Fast Screening for Purity and Adulterants in Coconut Oil by ASAP® Compact Mass Spectrometry

The expression CMS coupled with the Atmospheric Solids Analysis Probe (ASAP®) is used to determine purity and detect adulterants in coconut oil. In this application note, pure coconut oil is tested against a sample of coconut oil adulterated with canola oil for comparative data analysis and a fast and easy method for purity analysis.

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iASAP Analysis of Air-Sensitive Compounds via Inert Sampling Techniques

Many chemical reactions carried out by synthetic chemists involve air-sensitive compounds such as metal catalysts and organometallics and must therefore be carried out in a glove box or using a Schlenk line to prevent oxidation and hydrolysis. Sampling and transportation of these samples to a mass spectrometer by an Atmospheric Solids Analysis Probe (ASAP ®)…

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