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CheMS

CheMS Opening Screen
The CheMS user interface simplifies the mass spectrometry experience and makes it more accessible in chemistry and biochemistry laboratories.  The user interface allows users to quickly select the workflow and type of compound they wish to analyze in just a few clicks of the mouse and the software automatically optimizes the ion source and data acquisition parameters to ensure they get the data they need for decision-making. This allows the chemist to obtain optimal data without needing to be an expert in mass spectrometry.

Mass Express

Mass Express, the expression CMS software, was developed to provide chemists with answers in the fewest steps and shortest period of time possible in an easy-to-use interface. Whether your application is FIA/CMS, Flash/CMS, LC/CMS or flow reaction monitoring, the Mass Express data acquisition and workflow solutions are simple, inviting and efficient.

  • Simple software controlled from laptop
  • Contact closure or batch capability
  • 4 analogue outputs for fraction collection of 4 analytes

Peak Express™

Peak Express™, the latest addition to Advion’s Mass Express software, offers a new type of mass spectrum: the Delta Spectrum (ΔS). The patented ΔS is able to look beyond chemical noise and automatically detect even the smallest peaks without knowing the m/z. With Peak Express™ you can easily find adducts, dimers, fragments, side-reactions and other unexpected compounds at the click of a button, in real-time or with post-processing. The software highlights minor components in complex mixtures and dirty matrices, and can give you the ability to control mass-directed purification without providing the compound mass. Finally, users can easily acquire XIC-quality data while scanning the entire mass range, allowing Peak Express™ to tell you the m/z.

Quant Express

Quant Express, an addition to Advion’s user friendly Mass Express 4.1 software suite, is a full feature quantitation application for LC/MS data. The quantitation method can be configured in Mass Express before the analysis or in Quant Express post-analysis and it supports calibration curves, internal standards, QCs and unknowns using SIM or scan mode data. An enhanced peak detection algorithm ensures highest accuracy and ease of use.

Data Express

Data Express is the data processing software program which accomplishes the perfect balance: easily analyze and display results, or use a wealth of software resources to mine the data for accurate decision-making, archiving or exporting.

Far beyond lazy UV peaks with features due to unknown causes, Data Express delivers the exact information required to monitor reactions, confirm fractions of interest, speed workflow, and move on to the next research interest. Data Express exports net.cdf and .csv files for complete analytical consideration.

LC Integration

Advion now offers a streamlined (U)HPLC package for the seamless integration with the expression CMS.

For other solutions, integration with over 250 LC systems is accomplished with Clarity from DataApex, allowing chemists maximum flexibility and adaptability within their lab.  Features of the Clarity software include complete instrument control, data acquisition and processing, a full quantitation package, CFR21 part 11 compliance, and MS libraries.

Additionally, Mass Express offers direct integration with Agilent Technologies’ liquid chromatography systems. Using Agilents Instrument Control Framework (ICF), the user interface is identical to the Mass Hunter experience.

expression CMS Success Stories

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Mass Spectrometry Facility, Department of Chemistry University of Birmingham

“The Chemists are spending significantly more time running reactions.”

Chi Tsang, Experimental Officer

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Technical University Munich, Garching, Germany

“The expression CMS is the perfect MS system for any research laboratory involved in synthetic organic chemistry and chemical analytics or small molecules to proteins.”

Dr. Tobias A.M. Gulder, Professor

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New Path Molecular Ltd, United Kingdom

“expression CMS meets our requirements for an instrument that is intuitive to use, robust and capable of being maintained, expanded and serviced without manufacturer call outs.”

Dr. Gary Tarver, Lead Chemist

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Corden Pharma Switzerland LLC, Liestal, Switzerland

"We use the Advion expression CMS as a robust and versatile detector in our chromatographic processes, both MPLC and HPLC."

Dr. Markus Juza, Purification Expert

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Recent expression CMS Publications

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expression CMS Application Notes

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Toluene-Assisted APCI and Elemental Composition Prediction Using a Compact Mass Spectrometer

OVERVIEW Toluene-assisted APCI (TAPCI) can generate (M)+· and (M+H)+ ions from analytes that cannot be ionized by ESI or APCI. Elemental formula prediction at 250 ppm accuracy and isotope distribution matching by TAMI (Tal Aviv Molecule Identifier) supports analyte identification. Combining both TAPCI and TAMI on the expression compact mass spectrometer (CMS) provides a cost-effective…

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Rapid Screening for Fentanyl in Urine using the Advion expressionL CMS with the Touch Express™ Open Port Sampling Interface (OPSI)

Quick and easy analysis methods for drugs of abuse are in high demand from health practitioners and law enforcement agencies on a global scale. In 2017, it was found that fentanyl, a fast-acting synthetic painkiller that is nearly 100 times stronger than morphine, has become the most widely abused synthetic opioid medicine – to the…

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LC/CMS Determination of Polycyclic Aromatic Hydrocarbons (PAHS) in Water (EPA 610 Mix)

Polycyclic aromatic hydrocarbons (PAHs) are neutral compounds containing multiple aromatic fused rings that are present in fossil fuels and can be formed from the incomplete combustion of organic material. In recent years, it has been well documented that several PAHs can be potentially carcinogenic via exposure or ingestion. The EPA has classified seven PAHs (benzo[a]pyrene, benz[a]anthracene, chrysene, benzo[b]fluoranthene, benzo[k]fluoranthene, dibenz[a,h]anthracene, and indeno[1,2,3-cd]pyrene) as Group…

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Direct Analysis of Intact Proteins using the Advion Touch Express© Open Port Sampling Interface (OPSI) with the expressionL Compact Mass Spectrometer

Touch ExpressTM is a new sampling device for mass spec analysis using a technique developed by Gary Van Berkel and Vilmos Kertesz of Oak Ridge National Laboratory – the Open Port Sample Interface (OPSI). This fast, versatile sample inlet paired with the expression Compact Mass Spectrometer (CMS) provides simple molecular weight determination of surfaces, solids and liquids in < 30s.

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