Advion’s AVANT Chromatography Systems

expression CMS

The latest in chromatography solutions for compact mass spectrometry, the Advion AVANT series offers:

  • HPLC and UHPLC
  • UV and UV-Vis DAD
  • Modular and stackable design

PLUS Seamless integration with Advion’s expression Compact Mass Spectrometer.

Advion’s range of Avant, high performance, liquid chromatography systems can be used standalone with UV and UV/Vis detector options, or with the expression compact mass spectrometer to provide seamlessly integrated LC/CMS under the full control of Advion’s simple, intuitive Mass Express software suite.

Modular, stackable design, with many options, provides custom solutions for both HPLC and UHPLC needs. From the simplest manual injection HPLC to a fully automated, streamlined UHPLC system and everything in-between, the Avant series can be configured to fit your analytical requirements and your budget.

expression CMS

The Avant (U)HPLC series is the latest in Advion’s innovative line of sample inlet devices for the expression CMS which include:

  • Plate Express for automated mass assays from TLC plates,
  • The ASAP direct analysis probe for solid, liquid and even air sensitive, samples
  • vAPCI for analysis of volatile organic compounds (VOCs) from head spaces, breath, and other gas samples.
  • Flow chemistry interfaces

All these techniques can be simply, simultaneously, interfaced with the CMS so that the chemist can move quickly and effortlessly between workflows

expression CMS Success Stories

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University of Cambridge, Ley Group

“I would recommend the system to any group that works with continuous flow chemistry, especially those that need real time analysis of stream compositions.”

Daniel E. Fitzpatrick, Ph. D Candidate, Student Researcher & Founder, ChemInventory

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Research Analyst – University of Leiden

“I incorporated the expression CMS as a TLC/MS system because of its simplicity, low cost and the brilliant combination with the Plate Express.”

Dr. Hans van den Elst, Research Analyst, University of Leiden

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Department of Chemistry – Creighton University

“It’s easy, walk-up use with straightforward swapping of ESI and APCI sources make it a reliable, productive tool for determining synthetic success.”

Dr. Martin Hulce, Department of Chemistry, Creighton University

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Cyclotron and Radiochemistry Research Program – UNC School of Medicine

“The convenience of having a mass spectrometer in our laboratory means that we can increase working efficiencies.”

Dr. Zibo Li, Department of Radiology UNC School of Medicine

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Recent expression CMS Publications

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expression CMS Application Notes

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Fast Screening for Purity and Adulterants in Coconut Oil by ASAP® Compact Mass Spectrometry

The expressionL CMS coupled with the Atmospheric Solids Analysis Probe (ASAP®) is used to determine purity and detect adulterants in coconut oil. In this application note, pure coconut oil is tested against a sample of coconut oil adulterated with canola oil for comparative data analysis and a fast and easy method for purity analysis.

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iASAP Analysis of Air-Sensitive Compounds via Inert Sampling Techniques

Many chemical reactions carried out by synthetic chemists involve air-sensitive compounds such as metal catalysts and organometallics and must therefore be carried out in a glove box or using a Schlenk line to prevent oxidation and hydrolysis. Sampling and transportation of these samples to a mass spectrometer by an Atmospheric Solids Analysis Probe (ASAP ®)…

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Identification of a Pesticide Used in Lawn Care by vAPCI Compact Mass Spectrometry

At regular intervals throughout the year a local lawn service applies pesticides to the lawn surrounding the Advion headquarters in Ithaca, NY. The grass is very uniform and not a single dandelion or crabgrass plant is visible – so we wondered, what chemical do they use? After an application in the early spring, we sampled…

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Analyses of Different Grades of Olive Oil by Volatile Mass Spectrometry

In this application note, we demonstrate the use of the Advion expression CMS with a volatile APCI (vAPCI) ion source to analyze extra-virgin, virgin, and lampante olive oil samples. We show statistical analysis allowing us to categorize and identify olive oil samples by their grade. This technique allows us to test individual olive oil samples and…

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