Advion’s AVANT Chromatography Systems

expression CMS

The latest in chromatography solutions for compact mass spectrometry, the Advion AVANT series offers:

  • HPLC and UHPLC
  • UV and UV-Vis DAD
  • Modular and stackable design

PLUS Seamless integration with Advion’s expression Compact Mass Spectrometer.

Advion’s range of Avant, high performance, liquid chromatography systems can be used standalone with UV and UV/Vis detector options, or with the expression compact mass spectrometer to provide seamlessly integrated LC/CMS under the full control of Advion’s simple, intuitive Mass Express software suite.

Modular, stackable design, with many options, provides custom solutions for both HPLC and UHPLC needs. From the simplest manual injection HPLC to a fully automated, streamlined UHPLC system and everything in-between, the Avant series can be configured to fit your analytical requirements and your budget.

expression CMS

The Avant (U)HPLC series is the latest in Advion’s innovative line of sample inlet devices for the expression CMS which include:

• Plate Express for automated mass assays from TLC plates,

• The ASAP direct analysis probe for solid, liquid and even air sensitive, samples

• vAPCI for analysis of volatile organic compounds (VOCs) from head spaces, breath, and other gas samples.

• Flow chemistry interfaces

All these techniques can be simply, simultaneously, interfaced with the CMS so that the chemist can move quickly and effortlessly between workflows

 

expression CMS Success Stories

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Mass Spectrometry Facility, Department of Chemistry University of Birmingham

“The Chemists are spending significantly more time running reactions.”

Chi Tsang, Experimental Officer

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Technical University Munich, Garching, Germany

“The expression CMS is the perfect MS system for any research laboratory involved in synthetic organic chemistry and chemical analytics or small molecules to proteins.”

Dr. Tobias A.M. Gulder, Professor

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New Path Molecular Ltd, United Kingdom

“expression CMS meets our requirements for an instrument that is intuitive to use, robust and capable of being maintained, expanded and serviced without manufacturer call outs.”

Dr. Gary Tarver, Lead Chemist

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Corden Pharma Switzerland LLC, Liestal, Switzerland

"We use the Advion expression CMS as a robust and versatile detector in our chromatographic processes, both MPLC and HPLC."

Dr. Markus Juza, Purification Expert

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Recent expression CMS Publications

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expression CMS Application Notes

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Toluene-Assisted APCI and Elemental Composition Prediction Using a Compact Mass Spectrometer

OVERVIEW Toluene-assisted APCI (TAPCI) can generate (M)+· and (M+H)+ ions from analytes that cannot be ionized by ESI or APCI. Elemental formula prediction at 250 ppm accuracy and isotope distribution matching by TAMI (Tal Aviv Molecule Identifier) supports analyte identification. Combining both TAPCI and TAMI on the expression compact mass spectrometer (CMS) provides a cost-effective…

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Rapid Screening for Fentanyl in Urine using the Advion expressionL CMS with the Touch Express™ Open Port Sampling Interface (OPSI)

Quick and easy analysis methods for drugs of abuse are in high demand from health practitioners and law enforcement agencies on a global scale. In 2017, it was found that fentanyl, a fast-acting synthetic painkiller that is nearly 100 times stronger than morphine, has become the most widely abused synthetic opioid medicine – to the…

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LC/CMS Determination of Polycyclic Aromatic Hydrocarbons (PAHS) in Water (EPA 610 Mix)

Polycyclic aromatic hydrocarbons (PAHs) are neutral compounds containing multiple aromatic fused rings that are present in fossil fuels and can be formed from the incomplete combustion of organic material. In recent years, it has been well documented that several PAHs can be potentially carcinogenic via exposure or ingestion. The EPA has classified seven PAHs (benzo[a]pyrene, benz[a]anthracene, chrysene, benzo[b]fluoranthene, benzo[k]fluoranthene, dibenz[a,h]anthracene, and indeno[1,2,3-cd]pyrene) as Group…

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Direct Analysis of Intact Proteins using the Advion Touch Express© Open Port Sampling Interface (OPSI) with the expressionL Compact Mass Spectrometer

Touch ExpressTM is a new sampling device for mass spec analysis using a technique developed by Gary Van Berkel and Vilmos Kertesz of Oak Ridge National Laboratory – the Open Port Sample Interface (OPSI). This fast, versatile sample inlet paired with the expression Compact Mass Spectrometer (CMS) provides simple molecular weight determination of surfaces, solids and liquids in < 30s.

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