Specifications

  • Ion Source: ESI, APCI, or APCI/ASAP (direct analysis probe)
  • API interface: orthogonal ion sampling from heated capillary – allows for small single turbo pump (Patents pending)
  • Flow rate range: 10 µL/min to 1 mL/min ESI; 10 µL/min to 2 mL/min APCI
  • Polarity: Positive & Negative ion switching in single analysis
  • Polarity Switching Speed: 50 ms
  • m/z Range: -E model m/z 80 to m/z 800; -S model m/z 10 to m/z 1,200; -L model m/z 10 to m/z 2,000
  • Acquisition speed: 10,000 m/z units sec-1 (compatible with UHPLC)
  • Resolution: 0.5-0.7 m/z units (FWHM) at 1000 m/z units sec-1 over entire acquisition range
  • SIM sensitivity: 10 pg Reserpine (FIA – 5µL sample injection volume at 100 µL/min) 100:1 S/N (RMS) with SIM of m/z 609.28
  • Accuracy: ± 0.1 m/z units over entire acquisition range
  • Dynamic Range: 4.5 orders of magnitude

expression CMS Success Stories

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Mass Spectrometry Facility, Department of Chemistry University of Birmingham

“The Chemists are spending significantly more time running reactions.”

Chi Tsang, Experimental Officer

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Technical University Munich, Garching, Germany

“The expression CMS is the perfect MS system for any research laboratory involved in synthetic organic chemistry and chemical analytics or small molecules to proteins.”

Dr. Tobias A.M. Gulder, Professor

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New Path Molecular Ltd, United Kingdom

“expression CMS meets our requirements for an instrument that is intuitive to use, robust and capable of being maintained, expanded and serviced without manufacturer call outs.”

Dr. Gary Tarver, Lead Chemist

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Corden Pharma Switzerland LLC, Liestal, Switzerland

"We use the Advion expression CMS as a robust and versatile detector in our chromatographic processes, both MPLC and HPLC."

Dr. Markus Juza, Purification Expert

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Recent expression CMS Publications

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expression CMS Application Notes

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Toluene-Assisted APCI and Elemental Composition Prediction Using a Compact Mass Spectrometer

OVERVIEW Toluene-assisted APCI (TAPCI) can generate (M)+· and (M+H)+ ions from analytes that cannot be ionized by ESI or APCI. Elemental formula prediction at 250 ppm accuracy and isotope distribution matching by TAMI (Tal Aviv Molecule Identifier) supports analyte identification. Combining both TAPCI and TAMI on the expression compact mass spectrometer (CMS) provides a cost-effective…

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Rapid Screening for Fentanyl in Urine using the Advion expressionL CMS with the Touch Express™ Open Port Sampling Interface (OPSI)

Quick and easy analysis methods for drugs of abuse are in high demand from health practitioners and law enforcement agencies on a global scale. In 2017, it was found that fentanyl, a fast-acting synthetic painkiller that is nearly 100 times stronger than morphine, has become the most widely abused synthetic opioid medicine – to the…

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LC/CMS Determination of Polycyclic Aromatic Hydrocarbons (PAHS) in Water (EPA 610 Mix)

Polycyclic aromatic hydrocarbons (PAHs) are neutral compounds containing multiple aromatic fused rings that are present in fossil fuels and can be formed from the incomplete combustion of organic material. In recent years, it has been well documented that several PAHs can be potentially carcinogenic via exposure or ingestion. The EPA has classified seven PAHs (benzo[a]pyrene, benz[a]anthracene, chrysene, benzo[b]fluoranthene, benzo[k]fluoranthene, dibenz[a,h]anthracene, and indeno[1,2,3-cd]pyrene) as Group…

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Direct Analysis of Intact Proteins using the Advion Touch Express© Open Port Sampling Interface (OPSI) with the expressionL Compact Mass Spectrometer

Touch ExpressTM is a new sampling device for mass spec analysis using a technique developed by Gary Van Berkel and Vilmos Kertesz of Oak Ridge National Laboratory – the Open Port Sample Interface (OPSI). This fast, versatile sample inlet paired with the expression Compact Mass Spectrometer (CMS) provides simple molecular weight determination of surfaces, solids and liquids in < 30s.

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