Blog

February 20, 2015

expression CMS: Compact. Fast. Easy. & Affordable

With over 20 years of mass spectrometry and chemistry expertise, Advion has produced a family of compact mass spectrometers designed for the chemist. The affordability, small size and ease of use make them ideal for use directly at the chemist’s bench, giving immediate answers and informed decisions instead of waiting.

Download the brochure »
January 28, 2015

Expanded application note. DIRECT SAMPLE ANALYSIS: Detecting THC/Cannabinoids in Contraband by Compact Mass Spectrometry

This is an expanded application note with more data regarding direct sample analysis of THC in suspected contraband and on skin. Direct sample analysis is possible via an Atmospheric Solids Analysis Probe (ASAP®) combined with atmospheric pressure chemical ionization (APCI) on a compact mass spectrometer (CMS). This technique allows for the rapid investigation (<30 sec) of material suspected of containing THC/cannabinoids.

Download the application note »
January 28, 2015

Screening of explosives residues without sample preparation using a direct sample analysis probe on the expression CMS

The ability to effectively screen passengers with minimal personal contact is critical. Ion mobility detectors used at many airports can be inaccurate and provide many false-positives and false-negatives. Advanced Imaging Technology (AIT) screening techniques are very useful for detecting concealed weapons and explosive devices located on passengers and/or in their belongings, however are unable to detect trace amounts of explosive residues.

Download the application note »
January 7, 2015

Direct Sample Analysis: Detecting THC/Cannabinoids in Contraband by Compact Mass Spectrometry

Direct sample analysis is possible via an Atmospheric Solids Analysis Probe (ASAP®) combined with atmospheric pressure chemical ionization (APCI) on a compact mass spectrometer (CMS). This technique allows for the rapid investigation (<30 sec) of material suspected of containing THC/cannabinoids.

Download the application note »
December 30, 2014

Quantitative spatial analysis of the mouse brain lipidome by pressurized liquid extraction surface analysis (PLESA)

Reinaldo Almeida, Zane Berzina, Eva C. Arnspang, Jan Baumgart, Johannes Vogt, Robert Nitsch, and Christer S. Ejsing

Anal. Chem., Just Accepted Manuscript
DOI: 10.1021/ac503627z
Publication Date (Web): December 30, 2014
Copyright © 2014 American Chemical Society

 

Here we describe a novel surface sampling technique termed pressurized liquid extraction surface analysis (PLESA), which in combination with a dedicated high resolution shotgun lipidomics routine enables both quantification and in-depth structural characterization of molecular lipid species extracted directly from tissue sections.

Read the abstract »
December 18, 2014

Direct Sample Analysis of “Fizzy Drinks”

Chemists are tasked with quickly identifying compounds created, ensuring quality of products or evaluating safety. Current techniques are adequate, but not all offer speed, data quality or ease-of-use provided by the expression Compact Mass Spectrometer (CMS). The expression CMS with the direct analysis probe (ASAP®) offers chemists the ability to rapidly analyze solids, liquids and powders without tedious and time consuming sample preparation.

Download the application note »
December 9, 2014

Using the TriVersa NanoMate with LESA for Analyte Profiling in Material Science

Surface analysis techniques have gained significant attention over the last couple of years with LESA being an interesting alternative to techniques such as SIMS or MALDI imaging. A new application note demonstrates practical applications for LESA in the material sciences.

Download the application note »
December 9, 2014

LC/MS Determination of Amino Acids Using Compact Mass Spectrometry

See examples for the determination of amino acids on a combined HPLC compact mass spectrometry (LC/CMS) system for the rapid detection and quantification of amino acids utilizing a novel mixed mode LC column.

Download the application note »
December 9, 2014

“Essential for any Lipidomics Laboratory.”

Associate Professor Christer S. Ejsing at the University of Southern Denmark uses the TriVersa NanoMate, as an essential laboratory instrument, for the development and applications of Lipidomic technology.

Download the customer profile »
October 28, 2014

New publication: Direct analysis of intact proteins from Escherichia coli colonies by LESA mass spectrometry

Researchers in the UK have demonstrated the use of Liquid Extraction Surface Analysis (LESA) on the TriVersa NanoMate for top-down identification of proteins directly from living bacterial colonies grown in Petri dishes, without sample preparation. The method offers “improved sampling precision and could be useful for spatial profiling of bacterial colonies or analysis of contaminated surfaces.”

Read the article »
October 25, 2014

New Video: Direct Analysis of Liquids and Solids

Direct sample analysis of liquids, solids and powders without chromatography is as easy as it sounds, and provides mass spectral information within seconds. Our new video demonstrates analysis of a reaction mixture.

Watch the video »
October 25, 2014

Environmental Analysis: Quantitation of Perchlorate by Ion Chromatography with Supressed Conductivity on the expression CMS

The expression Compact Mass Spectrometer (CMS) provides lower detection limits and greater selectivity for Perchlorate compared to a conductivity detector (CD).

Download the application note »
October 20, 2014

“Anyone interested in volatiles will find the CMS is an excellent instrument for targeted analysis.”

Dr. James Reynolds’s group at the University of Loughborough conducts analysis of volatiles by direct breath analysis. The expression CMS allows for highly sensitive dermination of volatile species in breath with no preconcentration.

Read this case study »
September 23, 2014

Reaction Monitoring by Direct Analysis Probe on a Compact Mass Spectrometer

The expression CMS provides essential compound information quickly and improves the chemist’s workflow. The Atmospheric Solids Analysis Probe (ASAP) permits fast analysis of solid and liquid samples and is a simple, faster and lower cost alternative to LC/MS methods. This direct analysis probe method has been shown to be useful for the analysis of volatile and semivolatile compounds. ASAP is available as a combined ASAP-APCI source, or existing APCI sources can be easily modified to become dual APCI-ASAP capable.

Download the sample analysis »
September 8, 2014

“Everyone can use it, including students.”

Dr. Frédéric Schmidt’s group at the Institut Curie in Paris had previously given their samples to outside MS services for analysis and had to wait for the results. Incorporating Advion’s expression CMS into their lab allowed them to have a self-service option that everyone could use. And the new workflow sped up their process significantly.

Read this testimonial »
August 20, 2014

Peptide/Protein Analysis in Less than One Minute

The expression CMS is a high performance, easy-to-use single quadrupole mass spectrometer with a small footprint to fit in space restricted labs. Priced substantially lower than other available systems, the CMS brings the analytical benefits of FIA/CMS and LC/CMS within the reach of more scientists than ever before.

Download this application note »
August 19, 2014

Direct Mass Analysis from Solid & Liquid Samples

The expression CMS improves the chemist’s workflow by using a direct analysis probe, otherwise known as ASAP® (Atomospheric Solids Analysis Probe), to permit chemists affordable and reliable sample analysis of solid and liquid samples such as reaction mixtures, food samples, natural products and tablets.

Download the product note »
July 18, 2014

“The CMS is a rugged instrument.”

Dr. Albert Koulman, a Senior Investigative Scientist with MRC Human Nutrition Research, is developing methods to gather information about lipoproteins while looking at the lipid through online liquid/liquid extraction using the expression CMS as the detector.

Read this testimonial »
June 24, 2014

“The CMS is a very helpful instrument that has shorten product detection times.”

Professor Meng of the Beijing Institute of Technology uses mass spectrometry as a tool for synthetic intermediates. With a large number of products to run, Meng and his team needed to shorten product detection times.

Read this testimonial »
June 24, 2014

Determination of Emerging Nitrogenous Economic Adulterants in Milk Proteins by HPLC/Compact Mass Spectrometry

The ability to rapidly screen milk ingredients in the manufacturing plants for potential economic adulterants is becoming increasingly important.

A simpler and more cost-effective alternative for frontline screening has been developed.

Download this presentation »