Natural products

Compound ID and Structural Information with Limited Sample Preparation from Natural Products

Naturally occurring active ingredients are ideal chemical starting structures to improve upon in the pharmaceutical drug development process. The expression S offers a faster scan speed, online polarity switching and in-source CID to generate the information for compound identification and structural information of previously unknown natural product analytes. Combined with the Plate Express, it allows targeted mass spectrum generated from thin layer chromatography plates.

expression CMS Success Stories

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Liverpool School of Tropical Medicine

"You do not need to be an expert in mass spectrometry to generate very useful and meaningful data."

Sitthivut Charoensutthivarakul

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Recent expression CMS Publications

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expression CMS Application Notes

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Fast Screening for Purity and Adulterants in Coconut Oil by ASAP® Compact Mass Spectrometry

The expressionL CMS coupled with the Atmospheric Solids Analysis Probe (ASAP®) is used to determine purity and detect adulterants in coconut oil. In this application note, pure coconut oil is tested against a sample of coconut oil adulterated with canola oil for comparative data analysis and a fast and easy method for purity analysis.

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Identification of a Pesticide Used in Lawn Care by vAPCI Compact Mass Spectrometry

At regular intervals throughout the year a local lawn service applies pesticides to the lawn surrounding the Advion headquarters in Ithaca, NY. The grass is very uniform and not a single dandelion or crabgrass plant is visible – so we wondered, what chemical do they use? After an application in the early spring, we sampled…

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Screening of Dietary Supplements by ASAP® Compact Mass Spectrometry

In this application note, we demonstrate the use of the Advion expressionL CMS with an atmospheric solids analysis probe (ASAP) ion source to analyze two supplements (figure 1) that contain DMBA, a synthetic stimulant that has not been tested on humans. The substance is the chemical cousin to drug DBAA, which is currently banned by…

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Complete Reaction-Monitoring Solution

Reaction monitoring is a key aspect in a range of chemistry environments from chemical synthesis to drug discovery to understanding natural products and protein synthesis. To understand the optimal time to quench a reaction for maximum yield as well as to monitor a reaction real-time is vital to many medicinal and synthetic organic chemists. The…

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