Natural products

Compound ID and Structural Information with Limited Sample Preparation from Natural Products

Naturally occurring active ingredients are ideal chemical starting structures to improve upon in the pharmaceutical drug development process. The expression S offers a faster scan speed, online polarity switching and in-source CID to generate the information for compound identification and structural information of previously unknown natural product analytes. Combined with the Plate Express, it allows targeted mass spectrum generated from thin layer chromatography plates.

expression CMS Success Stories

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Technical University Munich, Garching, Germany

“The expression CMS is the perfect MS system for any research laboratory involved in synthetic organic chemistry and chemical analytics or small molecules to proteins.”

Dr. Tobias A.M. Gulder, Professor

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Max-Planck-Institut für Kohlenforschung, Department for Homogeneous Catalysis

“Rapid characterization of reaction products combined with the lowest effort of sample preparation”

List Research Group, Max-Planck-Institut für Kohlenforschung

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University of Ljubljana, Slovenia

"We recommend this to every medicinal chemistry department."

Dr. Janez Ilaš, Associate Professor, The Chair of Pharmaceutical Chemistry, Faculty of Pharmacy

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Liverpool School of Tropical Medicine (LSTM), United Kingdom

"You do not need to be an expert in mass spectrometry to generate very useful and meaningful data."

Sitthivut Charoensutthivarakul

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Recent expression CMS Publications

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expression CMS Application Notes

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Fast Identification of Artificial Vanilla Flavor in Vanilla Extract by ASAP® Compact Mass Spectrometry

The expression CMS coupled with the Atmospheric Solids Analysis Probe (ASAP®) is used to quickly identify the presence of artificial vanilla, as well as confirm the purity of products marketed as such. This technique provides a fast and easy method for purity analysis.

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Fast Screening for Purity and Adulterants in Coconut Oil by ASAP® Compact Mass Spectrometry

The expression CMS coupled with the Atmospheric Solids Analysis Probe (ASAP®) is used to determine purity and detect adulterants in coconut oil. In this application note, pure coconut oil is tested against a sample of coconut oil adulterated with canola oil for comparative data analysis and a fast and easy method for purity analysis.

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Analyses of Different Grades of Olive Oil by Volatile Mass Spectrometry

In this application note, we demonstrate the use of the Advion expression CMS with a volatile APCI (vAPCI) ion source to analyze extra-virgin, virgin, and lampante olive oil samples. We show statistical analysis allowing us to categorize and identify olive oil samples by their grade. This technique allows us to test individual olive oil samples and…

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Sudan Dyes Analysis Using Compact Mass Spectrometry with TLC Interface

Sudan Dyes are synthesized azo-dyes which are widely used to generate color in plastics, leather, fabrics, oil, waxes, etc. They are classified as Group 3 carcinogens by the International Agency for Research on Cancer (IARC) and are banned as food additives worldwide. However, in some countries these dyes are still occasionally used in order to…

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