More sensitivity than LC/MS/MS for metabolite identification and detection of low level, active or toxic metabolites.

  • Characterize “hot” radio-labeled LC fractions
  • Obtain structural information on trace-level metabolites by infusing collected HPLC fractions
  • Low flow rates enable signal averaging for improved signal-to-noise
  • Rapidly switch between mass spectrometer scan options to obtain positive ion, precursor ion, neutral loss scanning or MSn analysis as well as accurate mass
  • Faster analysis cycle than LC-MS, allows for large scale population screening e.g. inborn errors of metabolism

Recent TriVersa NanoMate Publications

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