Liquid Extraction Surface Analysis (LESA®)

Analyze surfaces of interest with a combination of micro liquid extraction and nano-electrospray mass spectrometry for spatially resolved information of small molecule drugs, endogenous lipids / metabolites and proteins.

  • Fast, simple and direct analysis from biological or technical surfaces of interest
  • Spatial resolution of 400 – 1000 µm
  • Highly sensitive analysis due to nano-electrospray ionization and extraction in only 1 µL of solvent
  • Spatially resolved lipidomics, metabolomics or small molecule drug analysis
  • Analysis of bacteria and fungi in culture
  • Biofilms from medical devices

Please also visit our technical resource page for details and examples.